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微血管减压术后危及生命的并发症:596 例连续病例的经验教训。

Life-threatening complications after microvascular decompression procedure: Lessons from a consecutive series of 596 patients.

机构信息

Department of Neurosurgery, Mianyang Central Hospital, Mianyang, Sichuan Province, China.

Department of Neurosurgery, Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, China.

出版信息

J Clin Neurosci. 2021 Apr;86:64-70. doi: 10.1016/j.jocn.2021.01.014. Epub 2021 Jan 29.

DOI:10.1016/j.jocn.2021.01.014
PMID:33775349
Abstract

The microvascular decompression procedure (MVD) is widely utilized on patients with neurovascular compression syndromes, such as trigeminal neuralgia, hemifacial spasm and glossopharyngeal neuralgia, which have failed medical therapy. However, surgical complications are an ongoing problem. We retrospectively reviewed a total of 596 patients undergoing MVD in the Affiliated Hospital of Qingdao University from January 2008 to December 2018. Furthermore, we discussed the cases with life-threatening complications to determine the potential causes, aiming to achieve the goal of safer microvascular decompression. There were seven cases with life-threatening complications. Of those complications, one was cerebellar infarction with acute hydrocephalus, one was infarction of the cerebellum and the brain stem with acute hydrocephalus and serious intracranial infection, two were cerebellar haematoma, one was multiple haemorrhage with acute hydrocephalus, one was supratentorial subdural haematoma, and one was cerebellar swelling with acute hydrocephalus. After therapy, one patient died, one was in a persistent vegetative state, and five were discharged from the hospital upon recovery. In brief, MVD is a safe operation, and life-threatening complications accompanying MVD are rare, but require attention. The causes of some life-threatening complications are still not completely clear. Surgeons should continuously improve surgical techniques and perioperative care to reduce potential risks.

摘要

微血管减压术(MVD)广泛应用于神经血管压迫综合征患者,如三叉神经痛、面肌痉挛和舌咽神经痛等,这些患者已经对药物治疗无效。然而,手术并发症一直是一个问题。我们回顾性分析了 2008 年 1 月至 2018 年 12 月在青岛大学附属医院接受 MVD 治疗的 596 例患者。此外,我们还讨论了有生命危险的并发症病例,以确定潜在原因,旨在实现更安全的微血管减压术目标。有 7 例出现危及生命的并发症。其中,1 例为小脑梗死伴急性脑积水,1 例为小脑和脑干梗死伴急性脑积水和严重颅内感染,2 例为小脑血肿,1 例为急性脑积水伴多处出血,1 例为幕上硬脑膜下血肿,1 例为小脑肿胀伴急性脑积水。经过治疗,1 例患者死亡,1 例患者处于持续植物状态,5 例患者康复出院。总之,MVD 是一种安全的手术,伴发 MVD 的危及生命的并发症罕见,但需要注意。一些危及生命的并发症的原因仍不完全清楚。外科医生应不断改进手术技术和围手术期护理,以降低潜在风险。

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