Wang Shilong, Li Jun, Dong Jiangtao, Wang Ganggang, Xu Haoxiang, Zhu Licang, Pan Lina, Xu Hui
Department of Neurosurgery, The First Affiliated Hospital of Shihezi University, No.107, Bei Er Road, Shihezi, 832000, Xinjiang, China.
Department of Dermatology, The First Affiliated Hospital of Shihezi University, Shihezi, 832000, China.
Eur J Med Res. 2025 Aug 5;30(1):709. doi: 10.1186/s40001-025-02970-0.
This study aimed to assess the efficacy of a modified cranial closure technique combined with bone cement in mitigating postoperative complications, particularly cerebrospinal fluid (CSF) leakage, following microvascular decompression (MVD) surgery.
A retrospective analysis was conducted on 234 patients who underwent MVD surgery at our institution from October 2017 to October 2024. The patients were divided into three groups based on closure methods: autologous bone with bone cement and titanium screw and plate (ABBC + TSP), autologous bone with bone cement (ABBC), and traditional cranial closure (TCC). Postoperative complications, including CSF leakage, intracranial infection, and subcutaneous effusion, were compared among the groups.
The incidence of CSF leakage was significantly lower in the modified groups (ABBC + TSP and ABBC) compared to the traditional group (2.5% and 1.8 vs. 27.0%, P < 0.001). Multivariate logistic regression analysis confirmed that the modified technique was an independent protective factor against CSF leakage (OR 0.138, p = 0.024). Additionally, the modified groups demonstrated significantly lower rates of intracranial infection, subcutaneous effusion, and postoperative headache (p < 0.05).
The modified cranial closure technique combined with bone cement significantly reducing postoperative complications in MVD surgery, particularly CSF leakage and intracranial infection, presenting a promising approach for optimizing surgical outcomes.
本研究旨在评估改良颅骨闭合技术联合骨水泥在减轻微血管减压术(MVD)术后并发症,特别是脑脊液(CSF)漏方面的疗效。
对2017年10月至2024年10月在我院接受MVD手术的234例患者进行回顾性分析。根据闭合方法将患者分为三组:自体骨联合骨水泥及钛螺钉和钛板(ABBC + TSP)、自体骨联合骨水泥(ABBC)和传统颅骨闭合(TCC)。比较各组术后并发症,包括脑脊液漏、颅内感染和皮下积液。
与传统组相比,改良组(ABBC + TSP和ABBC)脑脊液漏的发生率显著降低(2.5%和1.8% vs. 27.0%,P < 0.001)。多因素logistic回归分析证实,改良技术是预防脑脊液漏的独立保护因素(OR 0.138,p = 0.024)。此外,改良组的颅内感染、皮下积液和术后头痛发生率显著降低(p < 0.05)。
改良颅骨闭合技术联合骨水泥可显著降低MVD手术的术后并发症,特别是脑脊液漏和颅内感染,为优化手术效果提供了一种有前景的方法。