Boutellis N, Khanna R K, Pisella P-J, Arsene S
Service d'ophtalmologie, Centre Hospitalier Universitaire Régional de Bretonneau, 2, boulevard Tonnellé, 37044 Tours, France.
Service d'ophtalmologie, Centre Hospitalier Universitaire Régional de Bretonneau, 2, boulevard Tonnellé, 37044 Tours, France.
J Fr Ophtalmol. 2021 May;44(5):680-686. doi: 10.1016/j.jfo.2020.07.025. Epub 2021 Mar 26.
Abducens nerve palsy (ANP) is the most common oculomotor palsy. This study aimed to evaluate the efficacy of medial rectus recession with lateral rectus plication in patients with unilateral acquired ANP and to describe the etiologies of this condition.
Thirty-one patients were included in this retrospective single-center study conducted between 2000 and 2019 at the university research hospital in Tours. The following data were collected before and after surgery: diplopia, oculomotor deviations, ocular motility, and head posturing.
The mean age was 55.9±18.9 years and the mean postoperative follow-up was 11±4 months. Postoperatively, the patients had significant reduction in diplopia in primary position (P<0.001), in abduction of the affected eye (P<0.001) and in distance and near horizontal deviations (P<0.001). Abduction of the affected eye was significantly improved (P<0.001), but reduction in head posturing was insignificant (P=0.27). The etiologies were as follows: trauma (8 patients, 26%), neoplasm (6 patients, 16%), stroke-related (5 patients, 16%), compressive (5 patients, 16%), undetermined (5 patients, 16%) and inflammatory (2 patients, 6%).
Medial rectus recession with lateral rectus plication is an effective procedure in reducing diplopia and ocular deviation in unilateral acquired ANP and may be used as a first-line intervention regardless of the initial ocular motility limitation in abduction. The causes are mainly traumatic but remain undetermined in one case out of six.
展神经麻痹(ANP)是最常见的眼球运动麻痹。本研究旨在评估内直肌后徙联合外直肌折叠术治疗单侧后天性ANP患者的疗效,并描述该疾病的病因。
本回顾性单中心研究纳入了2000年至2019年在图尔大学研究医院接受治疗的31例患者。收集手术前后的以下数据:复视、眼球运动偏差、眼球运动和头位。
平均年龄为55.9±18.9岁,术后平均随访时间为11±4个月。术后,患者在原在位(P<0.001)、患眼外展(P<0.001)以及远距离和近距离水平偏差(P<0.001)时的复视明显减轻。患眼外展明显改善(P<0.001),但头位降低不明显(P=0.27)。病因如下:外伤(8例,26%)、肿瘤(6例,16%)与中风相关(5例,16%)、压迫性(5例,16%)、未明确(5例,16%)和炎症性(2例,6%)。
内直肌后徙联合外直肌折叠术是减少单侧后天性ANP复视和眼球偏差的有效方法,无论初始外展时眼球运动受限情况如何,均可作为一线干预措施。病因主要为外伤,但六分之一的病例病因仍未明确。