Department of Statistics, The Ohio State University, 1958 Neil Ave, Columbus, OH, 43210, USA; Translational Data Analytics Institute, The Ohio State University, 1760 Neil Ave, Columbus, OH, 43210, USA.
Department of Engineering and Public Policy, Carnegie Mellon University, 5000 Forbes Ave, Baker Hall 129, Pittsburgh, PA, 15213, USA.
Drug Alcohol Depend. 2021 May 1;222:108665. doi: 10.1016/j.drugalcdep.2021.108665. Epub 2021 Mar 18.
To describe the social network characteristics of pregnant women with opioid use disorder (OUD) and explore how changes in social relationships during pregnancy may influence substance use behaviors.
Between 2017 and 2018, we conducted an exploratory pilot study among 50 pregnant women with OUD. Participants completed a detailed social network inventory to describe the behaviors (e.g. substance-using), social support characteristics (e.g. financial, emotional, informational) and roles (e.g. family member, friend) of network members. The primary outcome was a self-reported decrease in substance use during pregnancy. Pearson correlations were used to test for associations between covariates reflecting different aspects of participants' social networks and decreased substance use during pregnancy.
Most participants (84.0 %) decreased substance use during pregnancy and stated that pregnancy motivated them to engage in treatment (94.0 %). Participants had a median of 8 (IQR: 4-18) network members with differing proportions of those who did and did not use substances. Pregnancy prompted participants to significantly increase contact with (26.4 % vs. 5.0 %), have increased support from (35.7 % vs. 7.5 %), and a have a feeling of increased closeness with (26.1 % vs. 3.3 %) network members who did not use substances. However, decreased substance use during pregnancy was most strongly (negatively) associated with the proportion of network members who used substances and provided informational support (r=-0.25, p = 0.08) and a feeling of closeness (r=-0.26, p = 0.08).
Our findings indicate that pregnancy has a profound influence on women's substance use behaviors and that changes in social relationships due to pregnancy may influence substance use.
描述患有阿片类药物使用障碍（OUD）的孕妇的社交网络特征，并探讨怀孕期间社交关系的变化如何影响物质使用行为。
在 2017 年至 2018 年期间，我们对 50 名患有 OUD 的孕妇进行了一项探索性试点研究。参与者完成了详细的社交网络清单，以描述网络成员的行为（例如物质使用）、社会支持特征（例如财务、情感、信息）和角色（例如家庭成员、朋友）。主要结局是自我报告的怀孕期间物质使用减少。Pearson 相关系数用于测试反映参与者社交网络不同方面的协变量与怀孕期间物质使用减少之间的关联。
大多数参与者（84.0%）在怀孕期间减少了物质使用，并表示怀孕促使他们接受治疗（94.0%）。参与者的社交网络成员中位数为 8（IQR：4-18），其中使用和不使用物质的成员比例不同。怀孕促使参与者与不使用物质的网络成员显著增加联系（26.4%对 5.0%）、获得更多支持（35.7%对 7.5%），并与不使用物质的网络成员感觉更亲近（26.1%对 3.3%）。然而，怀孕期间物质使用减少与使用物质的网络成员比例以及提供信息支持（r=-0.25，p=0.08）和亲近感（r=-0.26，p=0.08）呈最强（负）相关。
我们的研究结果表明，怀孕对女性的物质使用行为有深远影响，怀孕引起的社交关系变化可能会影响物质使用。
