Satarova D E, Korchagin V B
Antibiot Khimioter. 1988 Jan;33(1):33-7.
Dependence of the values defining the content of iodine sorbing admixtures in semisynthetic penicillins on pH, reaction time and drug aliquots was studied. On the basis of this study a general approach to development of procedures for determining iodine sorbing admixtures in semisynthetic penicillins was suggested. Procedures for determination of iodine sorbing admixtures in carbenicillin, carfecillin, ampicillin, oxacillin, azlocillin and ampiox were developed.
研究了半合成青霉素中碘吸附混合物含量定义值对pH、反应时间和药物等分试样的依赖性。基于该研究,提出了一种开发半合成青霉素中碘吸附混合物测定方法的通用方法。开发了羧苄青霉素、羧苄磺苄青霉素、氨苄青霉素、苯唑西林、阿洛西林和氨比西林中碘吸附混合物的测定方法。