Department of Cariology and Operative Dentistry, Tokyo Medical and Dental University.
Department of Operative Dentistry, Cariology and Pulp Biology, Tokyo Dental College.
Dent Mater J. 2021 Jul 31;40(4):1041-1048. doi: 10.4012/dmj.2020-290. Epub 2021 Mar 27.
This study evaluated the ability of different types of silver diammine fluoride (SDF) to inhibit dentin demineralization using micro-focused X-ray computed-tomography (µCT). Dentin specimens were divided into five groups (n=10); no-treatment (control), 3.8% SDF (RC), 38% SDF, 38% SDF with potassium iodide (SDF/KI), and potassium fluoride (KF). The treated-dentin surfaces were subjected to demineralization for 7-days and assessed using µCT to determine mineral loss (ML) values. Specimens were also analyzed with scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS). The ML values of the SDF and KF groups were significantly lower than those of the RC and SDF/KI groups. EDS detected fluoride ions in the SDF and KF groups but not in the RC and SDF/KI groups. It was concluded that 38% SDF demonstrated a high ability to inhibit dentin demineralization while additional application of KI may diminish the inhibitory effect of SDF. The amount of dentin demineralization with SDF treatments was material dependent.
本研究采用微焦点 X 射线计算机断层扫描（µCT）评估了不同类型的银双胺氟化物（SDF）抑制牙本质脱矿的能力。将牙本质标本分为五组（n=10）；无处理（对照）、3.8% SDF（RC）、38% SDF、38% SDF 加碘化钾（SDF/KI）和氟化钾（KF）。用 µCT 评估经处理的牙本质表面在 7 天内脱矿情况，以确定矿物质损失（ML）值。还使用扫描电子显微镜（SEM）和能量色散 X 射线光谱法（EDS）对标本进行分析。SDF 和 KF 组的 ML 值明显低于 RC 和 SDF/KI 组。EDS 在 SDF 和 KF 组中检测到氟离子，但在 RC 和 SDF/KI 组中未检测到。结论是 38% SDF 表现出很强的抑制牙本质脱矿能力，而额外添加 KI 可能会降低 SDF 的抑制效果。SDF 处理的牙本质脱矿量取决于材料。
