Department of Infectious Diseases, Nagoya University Hospital, Japan.
Department of Hematology, Japanese Red Cross Nagoya First Hospital, Japan.
Intern Med. 2021 Sep 15;60(18):3041-3045. doi: 10.2169/internalmedicine.6189-20. Epub 2021 Mar 29.
We herein report a 59-year-old woman with a 2-year history of chronic bursitis of the hand who took 50 mg/day prednisolone for several autoimmune diseases. Mycobacteroides abscessus subsp. massiliense was isolated from the abscess and blood culture. Combination therapy (imipenem/cilastatin, amikacin, and clarithromycin) was administered for a month. Two months later, M. massiliense was detected from a blood culture again, and disseminated lesions were found. Clarithromycin and sitafloxacin were administered following eight weeks of the same regimen. Six months after the diagnosis, M. massiliense was isolated from a blood culture, and she expired due to multiple organ failure.
我们在此报告一例 59 岁女性，手部慢性滑囊炎病史 2 年，因多种自身免疫性疾病每日服用 50mg 泼尼松龙。脓肿分枝杆菌亚种马萨利ensis 从脓肿和血培养中分离出来。给予联合治疗（亚胺培南/西司他丁、阿米卡星和克拉霉素）一个月。两个月后，血培养再次检测到 M. massiliense，发现播散性病变。在相同方案治疗 8 周后，给予克拉霉素和司他沙星。诊断后 6 个月，从血培养中分离出 M. massiliense，因多器官衰竭而死亡。
