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滑囊炎、菌血症和分枝杆菌(分枝杆菌)脓肿亚种的分枝杆菌属(分枝杆菌)的播散性感染。

Bursitis, Bacteremia, and Disseminated Infection of Mycobacteroides (Mycobacterium) abscessus subsp. massiliense.

机构信息

Department of Infectious Diseases, Nagoya University Hospital, Japan.

Department of Hematology, Japanese Red Cross Nagoya First Hospital, Japan.

出版信息

Intern Med. 2021 Sep 15;60(18):3041-3045. doi: 10.2169/internalmedicine.6189-20. Epub 2021 Mar 29.

Abstract

We herein report a 59-year-old woman with a 2-year history of chronic bursitis of the hand who took 50 mg/day prednisolone for several autoimmune diseases. Mycobacteroides abscessus subsp. massiliense was isolated from the abscess and blood culture. Combination therapy (imipenem/cilastatin, amikacin, and clarithromycin) was administered for a month. Two months later, M. massiliense was detected from a blood culture again, and disseminated lesions were found. Clarithromycin and sitafloxacin were administered following eight weeks of the same regimen. Six months after the diagnosis, M. massiliense was isolated from a blood culture, and she expired due to multiple organ failure.

摘要

我们在此报告一例 59 岁女性,手部慢性滑囊炎病史 2 年,因多种自身免疫性疾病每日服用 50mg 泼尼松龙。脓肿分枝杆菌亚种马萨利ensis 从脓肿和血培养中分离出来。给予联合治疗(亚胺培南/西司他丁、阿米卡星和克拉霉素)一个月。两个月后,血培养再次检测到 M. massiliense,发现播散性病变。在相同方案治疗 8 周后,给予克拉霉素和司他沙星。诊断后 6 个月,从血培养中分离出 M. massiliense,因多器官衰竭而死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a156/8502645/9ed08763a2e2/1349-7235-60-3041-g001.jpg

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