Oh Sung Jin
Department of Surgery, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Case Rep Oncol. 2021 Feb 23;14(1):67-72. doi: 10.1159/000507849. eCollection 2021 Jan-Apr.
Liver metastasis from gastric cancer has a very poor prognosis. Herein, we present two cases of liver metastases (synchronous and metachronous) from advanced gastric cancer. In the first case, the patient underwent radical subtotal gastrectomy. Liver metastases occurred 6 months after surgery while the patient was receiving adjuvant chemotherapy, but two hepatic tumors were successfully removed by radiofrequency ablation (RFA). In the second case, liver metastases occurred 15 months after surgery for gastric cancer. The patient also received RFA for one hepatic tumor, and other suspicious metastatic tumors were treated with systemic chemotherapy. Although these case presentations are limited for the efficacy of RFA treatment with systemic chemotherapy for hepatic metastases from gastric cancer, our findings showed long-term survival (overall survival for 108 and 67 months, respectively) of the affected patients, without recurrence. Therefore, we suggest that RFA treatment with systemic chemotherapy could be an effective alternative treatment modality for hepatic metastases from gastric cancer.
胃癌肝转移的预后非常差。在此，我们报告两例晚期胃癌肝转移（同时性和异时性）的病例。第一例中，患者接受了根治性胃次全切除术。术后6个月患者接受辅助化疗时发生肝转移，但通过射频消融（RFA）成功切除了两个肝肿瘤。第二例中，胃癌手术后15个月发生肝转移。该患者也对一个肝肿瘤进行了RFA治疗，其他可疑转移瘤采用全身化疗。尽管这些病例报告对于RFA联合全身化疗治疗胃癌肝转移的疗效有限，但我们的研究结果显示，受影响患者实现了长期生存（总生存期分别为108个月和67个月），且无复发。因此，我们认为RFA联合全身化疗可能是治疗胃癌肝转移的一种有效替代治疗方式。
