Bykov V L
Arkh Patol. 1988;50(2):39-42.
Histological changes of vaginal mucosa and portio vaginalis are described in women of reproductive age suffering from candidosis. The epithelial surface is covered with adherent masses composed of desquamated and destroyed epithelial cells and leukocytes impregnated with proteins and penetrated by pseudomycelium. The outer epithelial layers are characterized by dystrophic and necrobiotic changes, desquamation, formation of fissures and small cavities. Pseudomycelium penetrates 4 to 6 layers of the epithelium. The barrier between the invading pathogen and the blood vessels of the lamina propria papillae in some sites is only 5-6 flattened epithelial cells thick. In the basal layer, high mitotic activity is noted. Lamina propria contains lympho-plasmocytic infiltrates.
描述了患有念珠菌病的育龄女性阴道黏膜和阴道部的组织学变化。上皮表面覆盖着由脱落和破坏的上皮细胞以及充满蛋白质并被假菌丝穿透的白细胞组成的附着团块。外层上皮具有营养不良和坏死性变化、脱屑、裂隙和小腔形成。假菌丝穿透上皮的4至6层。在某些部位，入侵病原体与固有层乳头血管之间的屏障仅为5 - 6层扁平上皮细胞厚。在基底层，观察到高有丝分裂活性。固有层含有淋巴细胞 - 浆细胞浸润。
