Department of Neurology, Cheikh Khalifa International University Hospital, Faculty of Medicine, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
Emergency Department, Mohamed V Military Hospital, Mohamed V University of Rabat, Rabat, Morocco.
Pan Afr Med J. 2021 Jan 13;38:34. doi: 10.11604/pamj.2021.38.34.27645. eCollection 2021.
Since December 2019, the world has experienced the emergence in China of a new infection called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This infection quickly has progressed to a global pandemic since March 2020, with very high human-to-human transmission rate. Besides lung injury, COVID-19 is also associated with cardio and neurovascular complications. Herein, we report the case of a 77-year-old female who presented with non-severe COVID-19 and multiple ischemic strokes secondary to an extensive carotid thrombosis. The ischemic stroke was supposed to have been caused by the cytokine storm related to COVID-19. The possibility of hemorrhagic transformation, based on the assessment of bleeding score, limited the use of anticoagulation, and probably explained the stroke recurrence and poor outcome in our patient. The pathogenic mechanism and the management of this complex situation are still lacking and further studies are needed.
自 2019 年 12 月以来，全球经历了一种新型感染，称为严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）。自 2020 年 3 月以来，这种感染迅速蔓延成为全球大流行，具有非常高的人际传播率。除了肺部损伤，COVID-19 还与心血管和神经血管并发症有关。在此，我们报告了一例 77 岁女性患者的病例，她患有非严重的 COVID-19 和多发性缺血性中风，继发于广泛的颈动脉血栓形成。缺血性中风可能是由 COVID-19 引起的细胞因子风暴引起的。根据出血评分评估，存在出血转化的可能性，限制了抗凝的使用，这可能解释了我们患者的中风复发和不良结局。这种复杂情况的发病机制和管理仍不清楚，需要进一步研究。
