Department of Dermatology, Aga Khan University Hospital, Karachi, Pakistan.
Sultan Qaboos Univ Med J. 2021 Feb;21(1):e124-e126. doi: 10.18295/squmj.2021.21.01.018. Epub 2021 Mar 15.
Verrucous epidermal nevi (VEN) are benign congenital hamartomas consisting of keratinocytes. Histological examination mostly exhibits hyperkeratosis, acanthosis, papillomatosis and, rarely, the features of epidermolytic hyperkeratosis (EHK). We report a case of a 6-year-old boy who presented at Aga Khan University Hospital, Karachi, Pakistan with bilaterally symmetrical linear epidermal nevi following Blaschko's lines and showing epidermolytic hyperkeratosis on histology. The patient was treated with topical keratolytics and emolients which led to considerable improvement. To the best of the authors' knowledge, this is the first report of VEN from Pakistan.
疣状表皮痣（VEN）是由角朊细胞组成的良性先天性错构瘤。组织学检查主要表现为角化过度、棘层肥厚、乳头瘤样增生，很少出现表皮松解性角化过度（EHK）的特征。我们报告了一例 6 岁男孩的病例，该病例在巴基斯坦卡拉奇的 Aga Khan 大学医院就诊，表现为双侧对称的线性表皮痣，沿 Blaschko 线分布，组织学表现为表皮松解性角化过度。患者接受了局部角质松解剂和保湿剂治疗，取得了显著改善。据作者所知，这是巴基斯坦首例 VEN 的报道。
