Programa de Pós-Graduação em Biodiversidade e Conservação da Natureza, Universidade Federal de Juiz de Fora, Juiz de Fora, Brazil.
Laboratório de Referência Nacional em Vetores das Riquetsioses- Secretaria de Vigilância em Saúde/Ministério da Saúde, Instituto Oswaldo Cruz/Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Front Public Health. 2021 Mar 12;9:577789. doi: 10.3389/fpubh.2021.577789. eCollection 2021.
Spotted Fever Rickettsioses (SFR) are diseases caused by bacteria of the genus , and are transmitted mainly by ticks. Its eco-epidemiological scenarios vary spatially, and may also vary over time due to environmental changes. It is the main disease transmitted by ticks to humans in Brazil, with the state of Paraná (PR) having the sixth highest number of notified incidences in the country. However, information is lacking regarding the SFR disease cycles at likely infection sites within PR. During case investigations or environmental surveillance in PR for SFR, 28,517 arthropods were collected, including species known or potentially involved in the SFR cycles, such as , and sensu lato. From these strain Atlantic Rainforest and Rickettsia paranaensis were detected. Ectoparasite abundance was found to be related with specific hosts and collection environments. Rickettsiae circulation was observed for 48 municipalities, encompassing 16 Health Regions (HR). As for socio-demographic and assistance indicators, circulation occurred largely in the most urbanized HR, with a higher per capita Gross Domestic Product, lower Family Health Strategy coverage, and with a higher ratio of beds in the Unified Health System per thousand inhabitants. For environmental variables, circulation occurred predominantly in HR with a climatic classified as "subtropical with hot summers" (Cfa), and with forest type phytogeographic formations. In terms of land use, circulation was commonest in areas with agriculture, pasture and fields and forest cover. Rickettsiae were circulating in almost all hydrographic basins of PR state. The results of this study provide the first descriptive recognition of SFR in PR, as well as outlining its eco-epidemiological dynamics. These proved to be quite heterogeneous, and analyzed scenarios showed characteristics strongly-associated with the outbreaks, with cases presenting clinical variation in space, so illustrating the complexity of scenarios in PR state. Due to the diversity of the circumstances surrounding SFR infections in PR, public health initiatives are necessary to foster a better understanding of the dynamics and factors effecting vulnerability to SFR in this Brazilian state.
斑点热立克次体病（SFR）是由 属细菌引起的疾病，主要通过蜱传播。其生态流行病学情景在空间上有所不同，也可能因环境变化而随时间变化。它是巴西主要通过蜱传播给人类的疾病，巴拉那州（PR）的报告病例数在全国排名第六。然而，关于 PR 中可能的感染地点的 SFR 疾病循环信息却很缺乏。在 PR 进行 SFR 的病例调查或环境监测期间，共收集了 28517 只节肢动物，包括已知或可能参与 SFR 循环的物种，如 和 sensu lato。从这些节肢动物中检测到了 株大西洋雨林立克次体和 巴拉那立克次体。外寄生虫的丰度与特定的宿主和采集环境有关。观察到 48 个城市的 立克次体循环，涵盖了 16 个卫生区域（HR）。就社会人口学和援助指标而言，循环主要发生在人口最城市化的 HR 中，人均国内生产总值较高，家庭健康战略覆盖率较低，每千名居民拥有的统一卫生系统床位比例较高。对于环境变量，循环主要发生在气候被归类为“夏季炎热的亚热带”（Cfa）的 HR 中，以及森林类型的植物地理形成。在土地利用方面，循环最常见于农业、牧场和农田以及森林覆盖的地区。PR 州的几乎所有水文流域都有 立克次体循环。这项研究的结果首次描述了 PR 州的 SFR，并概述了其生态流行病学动态。这些动态非常多样化，分析情景显示出与疫情强烈相关的特征，病例在空间上呈现出临床变化，因此说明了 PR 州疫情的复杂性。由于 PR 州 SFR 感染的情况多种多样，因此需要采取公共卫生措施，以更好地了解该州 SFR 动态和影响脆弱性的因素。
