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Performance of Antipseudomonal β-Lactams on the Accelerate PhenoTest BC Kit against a Collection of Pseudomonas aeruginosa Isolates.抗假单胞菌β-内酰胺类药物在Accelerate PhenoTest BC试剂盒上对一批铜绿假单胞菌分离株的性能表现。
J Clin Microbiol. 2021 Jan 21;59(2). doi: 10.1128/JCM.01781-20.
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Management of Gram-Negative Bloodstream Infections in the Era of Rapid Diagnostic Testing: Impact With and Without Antibiotic Stewardship.快速诊断检测时代革兰氏阴性菌血流感染的管理：有无抗生素管理的影响
Open Forum Infect Dis. 2020 Sep 12;7(10):ofaa427. doi: 10.1093/ofid/ofaa427. eCollection 2020 Oct.
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Update on Susceptibility Testing: Genotypic and Phenotypic Methods.更新药敏检测方法：表型和基因型方法。
Clin Lab Med. 2020 Dec;40(4):433-446. doi: 10.1016/j.cll.2020.08.002. Epub 2020 Sep 30.
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Time to Result for Pathogen Identification and Antimicrobial Susceptibility Testing of Bronchoalveolar Lavage and Endotracheal Aspirate Specimens in U.S. Acute Care Hospitals.美国急症护理医院中支气管肺泡灌洗液和气管内抽吸物标本的病原体鉴定和药敏试验的结果时间。
J Clin Microbiol. 2020 Oct 21;58(11). doi: 10.1128/JCM.01468-20.
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Clinical Performance and Impact of Accelerate Pheno for Gram-negative Bacteremia in Hospitalized Children.临床性能和对住院儿童革兰氏阴性菌血症的加速表型的影响。
Clin Ther. 2020 Sep;42(9):1630-1636. doi: 10.1016/j.clinthera.2020.07.015. Epub 2020 Aug 18.
6
EUCAST rapid antimicrobial susceptibility testing (RAST) in blood cultures: validation in 55 European laboratories.EUCAST 快速抗微生物药物敏感性检测（RAST）在血培养中的应用：55 个欧洲实验室的验证。
J Antimicrob Chemother. 2020 Nov 1;75(11):3230-3238. doi: 10.1093/jac/dkaa333.
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High Burden of Bloodstream Infections Associated With Antimicrobial Resistance and Mortality in the Neonatal Intensive Care Unit in Pune, India.印度浦那新生儿重症监护病房血流感染负担高，与抗菌药物耐药性和死亡率相关。
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Randomized Trial Evaluating Clinical Impact of RAPid IDentification and Susceptibility Testing for Gram-negative Bacteremia: RAPIDS-GN.随机试验评估革兰氏阴性菌血培养快速鉴定和药敏检测的临床影响：RAPIDS-GN。
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Rapid identification of bloodstream bacterial and fungal pathogens and their antibiotic resistance determinants from positively flagged blood cultures using the BioFire FilmArray blood culture identification panel.采用 BioFire FilmArray 血培养鉴定试剂盒，从阳性血培养物中快速鉴定血流细菌和真菌病原体及其抗生素耐药决定因素。
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血培养的快速抗菌药物敏感性检测方法及其临床影响

Rapid Antimicrobial Susceptibility Testing Methods for Blood Cultures and Their Clinical Impact.

作者信息

Banerjee Ritu, Humphries Romney

机构信息

Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.

Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, United States.

出版信息

Front Med (Lausanne). 2021 Mar 10;8:635831. doi: 10.3389/fmed.2021.635831. eCollection 2021.

DOI:10.3389/fmed.2021.635831
PMID:33777978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7987685/
Abstract

Antimicrobial susceptibility testing (AST) of bacteria isolated in blood cultures is critical for optimal management of patients with sepsis. This review describes new and emerging phenotypic and genotypic AST methods and summarizes the evidence that implementation of these methods can impact clinical outcomes of patients with bloodstream infections.

摘要

对血培养中分离出的细菌进行抗菌药物敏感性测试（AST）对于脓毒症患者的优化管理至关重要。本综述描述了新出现的表型和基因型AST方法，并总结了实施这些方法可影响血流感染患者临床结局的证据。