Wu Hao-Yu, Gao Tian-Jiao, Cao Yi-Wei, Liang Lei
Department of Cardiology, Shaanxi Provincial People's Hospital, Xi'an, China.
Department of Gastroenterology, Xi'an Children's Hospital, Xi'an, China.
Front Cardiovasc Med. 2021 Mar 11;8:648725. doi: 10.3389/fcvm.2021.648725. eCollection 2021.
Pheochromocytoma patients who present with shock are extremely rare. Here, we report a patient who presented with shock and was diagnosed with pheochromocytoma. A 59-year-old woman with a history of hypertension without any treatment for 5 years presented with chest tightness. Vital signs on arrival indicated blood pressure of 78/50 mmHg. Twelve-lead electrocardiogram indicated ST-segment depression in leads II, III, aVF, and V3-V6 and QT prolongation. Coronary angiogram revealed no evidence of coronary artery disease. Contrast-enhanced computed tomography demonstrated an inhomogeneous right adrenal mass (2.5 × 3.0 cm). Her 24-h urinary norepinephrine and catecholamine levels were elevated. The patient underwent laparoscopic right adrenalectomy. Histopathology confirmed adrenal pheochromocytoma with residual necrosis. The patient was diagnosed with pheochromocytoma. During the 2-year follow-up, the patient was asymptomatic, and her blood pressure remained normal without medication. ECG showed that the ST-segment depression in leads II, III, aVF, and V3-V6 and the QT prolongation had disappeared. The patient showed no signs of recurrence, with normal urine norepinephrine and catecholamine levels. Patients with pheochromocytoma can present with hypotension or even shock. Clinicians should suspect pheochromocytoma when a patient with a history of hypertension has sudden hypotension or even shock.
表现为休克的嗜铬细胞瘤患者极为罕见。在此,我们报告一例表现为休克且被诊断为嗜铬细胞瘤的患者。一名59岁女性,有5年高血压病史且未接受任何治疗,出现胸闷症状。入院时生命体征显示血压为78/50 mmHg。十二导联心电图显示II、III、aVF及V3 - V6导联ST段压低及QT间期延长。冠状动脉造影未发现冠状动脉疾病证据。增强CT显示右侧肾上腺有一不均匀肿块(2.5×3.0 cm)。她的24小时尿去甲肾上腺素和儿茶酚胺水平升高。患者接受了腹腔镜下右侧肾上腺切除术。组织病理学证实为肾上腺嗜铬细胞瘤伴残留坏死。该患者被诊断为嗜铬细胞瘤。在2年的随访中,患者无症状,血压无需药物治疗即保持正常。心电图显示II、III、aVF及V3 - V6导联ST段压低及QT间期延长消失。患者无复发迹象,尿去甲肾上腺素和儿茶酚胺水平正常。嗜铬细胞瘤患者可表现为低血压甚至休克。当有高血压病史的患者突然出现低血压甚至休克时,临床医生应怀疑嗜铬细胞瘤。