Adeleye Olutayo Ademola, Femi-Oyewo Mbang Nyong, Bamiro Oluyemisi Adebowale, Bakre Lateef Gbenga, Alabi Akinyinka, Ashidi Joseph Senu, Balogun-Agbaje Olalekan Adeyinka, Hassan Oluwakemi Mary, Fakoya Gbemisola
Department of Pharmaceutics and Pharmaceutical Technology, Federal University Oye Ekiti, Oye-Ekiti, Ekiti State Nigeria.
Department of Pharmaceutics and Pharmaceutical Technology, Olabisi Onabanjo University, Ago-Iwoye, Ogun State Nigeria.
Futur J Pharm Sci. 2021;7(1):72. doi: 10.1186/s43094-021-00223-5. Epub 2021 Mar 20.
Ethnomedicine, a study of traditional medicine, is significant in drug discovery and development. African traditional medicine has been in existence for several thousands of years, and several drugs have been discovered and developed from it.
The deadly coronavirus disease 2019 (COVID-19) caused by a novel coronavirus known as SARS-CoV-2 has widely spread globally with high mortality and morbidity. Its prevention, treatment and management still pose a serious challenge. A drug for the cure of this disease is yet to be developed. The clinical management at present is based on symptomatic treatment as presented by individuals infected and this is by combination of more than two drugs such as antioxidants, anti-inflammatory, anti-pyretic, and anti-microbials. Literature search was performed through electronic searches of PubMed, Google Scholar, and several research reports including WHO technical documents and monographs.
Drug discovery from herbs is essential and should be exploited for the discovery of drugs for the management of COVID-19. This review is aimed at identifying ethnomedicinal herbs available in Africa that could be used for the discovery and development of a drug for the prevention, treatment, and management of the novel coronavirus disease 2019.
民族医学作为对传统医学的研究，在药物发现和开发中具有重要意义。非洲传统医学已经存在了数千年，并且已经从中发现并开发了多种药物。
由一种名为严重急性呼吸综合征冠状病毒2型（SARS-CoV-2）的新型冠状病毒引起的致命的2019冠状病毒病（COVID-19）已在全球广泛传播，死亡率和发病率都很高。其预防、治疗和管理仍然构成严峻挑战。治疗这种疾病的药物尚未研发出来。目前的临床管理是基于感染者出现的症状进行对症治疗，这是通过两种以上药物的组合，如抗氧化剂、抗炎药、退烧药和抗菌药。通过对PubMed、谷歌学术以及包括世界卫生组织技术文件和专著在内的几份研究报告进行电子检索来开展文献检索。
从草药中发现药物至关重要，应利用其来发现用于管理COVID-19的药物。本综述旨在确定非洲现有的民族药用草药，这些草药可用于发现和开发预防、治疗和管理2019新型冠状病毒病的药物。
