Schollin J, Danielsson D
Department of Pediatrics, Orebro Medical Center Hospital, Sweden.
APMIS. 1988 May;96(5):428-32. doi: 10.1111/j.1699-0463.1988.tb05326.x.
Endothelial cells were prepared from rat heart, and the ability of various bacterial species to adhere to these cells was investigated, with special regard to alpha-hemolytic streptococci. The endothelial cells were identified by morphology and by the presence of F VIII antigen. Seventeen bacterial strains representing various species were used in the in vitro adherence tests; 10 strains represented various strains of alpha-hemolytic streptococci, 5 of which were isolated from patients with infective endocarditis and 5 from the throats of healthy individuals; 2 were Neisseria meningitidis, 2 N. gonorrhoeae, 2 S. aureus and 1 E. coli. The highest adherence rate was found for alpha-hemolytic streptococci isolated from patients with infective endocarditis. The difference compared to carrier strains of alpha-hemolytic streptococci and to the other tested strains was statistically highly significant.
从大鼠心脏制备内皮细胞，并研究了各种细菌对这些细胞的黏附能力，特别关注α-溶血性链球菌。通过形态学和F VIII抗原的存在来鉴定内皮细胞。在体外黏附试验中使用了代表各种菌种的17株细菌；10株代表各种α-溶血性链球菌菌株，其中5株从感染性心内膜炎患者中分离得到，5株从健康个体的咽喉中分离得到；2株是脑膜炎奈瑟菌，2株是淋病奈瑟菌，2株是金黄色葡萄球菌，1株是大肠杆菌。从感染性心内膜炎患者中分离出的α-溶血性链球菌黏附率最高。与α-溶血性链球菌带菌菌株和其他测试菌株相比，差异具有高度统计学意义。
