Veterinary Medicine Department, University of Bari Aldo Moro, Valenzano, Bari, 70010, Italy.
Department of Microbiology and Immunology, National Research Centre, Cairo, Egypt.
Zoonoses Public Health. 2021 Jun;68(4):316-326. doi: 10.1111/zph.12827. Epub 2021 Mar 29.
Bartonellae are emerging vector-borne pathogens infecting humans, domestic mammals and wildlife. Ninety-seven red foxes (Vulpes vulpes), 8 European badgers (Meles meles), 6 Eurasian wolves (Canis lupus), 6 European hedgehogs (Erinaceus europaeus), 3 beech martens (Martes foina) and 2 roe deer (Capreolus capreolus) from Italian Nature Conservatory Parks were investigated for Bartonella infection. Several Bartonella species (9.84%; 95% CI: 4.55-15.12), including zoonotic ones, were molecularly detected among wolves (83.3%; 95% CI: 51-100.00), foxes (4.12%; 95% CI: 0.17-8.08), hedgehogs (33.33%; 95% CI: 0.00-71.05) and a roe deer. Bartonella rochalimae was the most common Bartonella species (i.e. in 4 foxes and 2 wolves) detected. Candidatus B. merieuxii and B. vinsonii subsp. berkhoffii were identified for the first time in wolves. Furthermore, Bartonella schoenbuchensis was identified in a roe deer and a new clone with phylogenetic proximity to B. clarridgeiae was detected in European hedgehogs. Zoonotic and other Bartonella species were significantly more frequent in Eurasian wolves (p < .0001), than in other free-ranging wild mammals, representing a potential reservoir for infection in humans and domestic animals.
贝氏杆菌属是新兴的经媒介传播的病原体，感染人类、家畜和野生动物。从意大利自然保护公园的 97 只红狐（Vulpes vulpes）、8 只欧洲獾（Meles meles）、6 只欧亚狼（Canis lupus）、6 只欧洲刺猬（Erinaceus europaeus）、3 只山猫（Martes foina）和 2 只獐鹿（Capreolus capreolus）中调查了贝氏杆菌感染情况。在狼（83.3%；95%CI：51-100.00）、狐狸（4.12%；95%CI：0.17-8.08）、刺猬（33.33%；95%CI：0.00-71.05）和一只獐鹿中，分子检测到几种贝氏杆菌属（9.84%；95%CI：4.55-15.12），包括人畜共患病。首次在狼中鉴定出贝氏疏螺旋体（Bartonella rochalimae）和巴尔通体贝氏亚种（Bartonella vinsonii subsp. berkhoffii）。此外，在一只獐鹿和一只欧洲刺猬中鉴定出了巴尔通体舒恩拜因氏菌（Bartonella schoenbuchensis），并检测到一种与巴尔通体克拉里吉氏亚种亲缘关系较近的新克隆。在欧亚狼中，人畜共患病和其他贝氏杆菌属的频率明显高于其他自由放养的野生动物（p<0.0001），代表了人类和家畜感染的潜在传染源。
