Spinelli Claudio, Morelli Girolamo, Cito Gianmartin, Bertocchini Alessia, Ghionzoli Marco, Pucci Angela, Cocci Andrea, Morganti Riccardo, Strambi Silvia
Pediatric and Adolescent Surgery Division, Department of Medical, Molecular and Pathology Surgery, University of Pisa, Pisa, Italy.
Department of Urology and Andrology Surgery, University of Pisa, Pisa, Italy.
Urologia. 2022 May;89(2):292-297. doi: 10.1177/03915603211004732. Epub 2021 Mar 29.
Our aim is to assess the correlation between testicular volume and histological findings in children with unilateral cryptorchidism.
From September 2016 to August 2018, from 60 patients surgically treated for cryptorchidism, 45 children were enrolled in this single-center prospective study. Depending on the degree of testicular volume reduction, patients were divided into Group 1 with <20% reduction and Group 2 with reduction ⩾20%. Patients underwent unilateral orchidopexy and simultaneous biopsy of the undescended testis. Tanner stage was assigned. Tubular Fertility Index was measured.
Group 1 included 20 patients (44.4%) and Group 2 included 25 patients (55.5%). Mean age was 2.10 years (range 12 months-3.8 years) in Group 1 and 2.8 years (range 18 months-4.41 years) in Group 2. Although there is a positive correlation between testicular volume and Tubular Fertility Index, no significant association was found between groups (-value = 0.29). Furthermore, histological patterns did not differ significantly among groups.
The degree of volume reduction in undescended testis does not seem to correlate significantly with the severity of histological changes that accompany cryptorchidism. Tubular Fertility Index could serve as objective tool for the assessment of future fertility.
我们的目的是评估单侧隐睾症患儿睾丸体积与组织学检查结果之间的相关性。
2016年9月至2018年8月，在60例接受隐睾症手术治疗的患者中，45例儿童纳入了这项单中心前瞻性研究。根据睾丸体积缩小程度，患者分为睾丸体积缩小<20%的1组和睾丸体积缩小≥20%的2组。患者接受单侧睾丸固定术并同时对未降睾丸进行活检。确定坦纳分期。测量管状生育指数。
1组包括20例患者（44.4%），2组包括25例患者（55.5%）。1组平均年龄为2.10岁（范围12个月至3.8岁），2组平均年龄为2.8岁（范围18个月至4.41岁）。虽然睾丸体积与管状生育指数之间存在正相关，但两组之间未发现显著关联（P值=0.29）。此外，各组之间的组织学模式无显著差异。
未降睾丸的体积缩小程度似乎与隐睾症伴随的组织学变化严重程度无显著相关性。管状生育指数可作为评估未来生育能力的客观工具。
