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早期单眼剥夺后灵长类外侧膝状核中央和中央周围表征中细胞大小变化的比较。

A comparison of cell size changes in central and pericentral representations within the primate lateral geniculate nucleus following early monocular deprivation.

作者信息

Sloper J J, Headon M P, Powell T P

机构信息

Department of Human Anatomy, University of Oxford, U.K.

出版信息

Brain Res. 1988 May 1;468(1):61-4. doi: 10.1016/0165-3806(88)90007-7.

DOI:10.1016/0165-3806(88)90007-7
PMID:3378187
Abstract

Mean cell areas have been measured in the most posterior part of the lateral geniculate nucleus containing the representation of central retina in 8 normal monkeys (Macaca mulatta) and in 5 monkeys following monocular closure from birth. Comparisons with cell size changes at a more anterior level, where pericentral retina is represented, show that size changes of parvocellular cells at the posterior level are significantly less, being only between half and two-thirds of those more anteriorly. The undeprived cells undergo less initial hypertrophy than cells at a more anterior level and subsequently the deprived cells show less shrinkage. There is no comparable difference for magnocellular cells.

摘要

已对8只正常猴子(恒河猴)外侧膝状核中包含中央视网膜表征的最后部区域的平均细胞面积进行了测量,并对5只自出生起就单眼闭合的猴子进行了测量。与更靠前水平(代表周边视网膜)的细胞大小变化进行比较,结果显示,后部水平的小细胞大小变化明显较小,仅为更靠前水平变化的一半至三分之二。未受剥夺的细胞初始肥大程度低于更靠前水平的细胞,随后,受剥夺的细胞萎缩程度也较小。大细胞则没有类似差异。

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