Chang Hyejin, Kim Jaehi, Rho Won-Yeop, Pham Xuan-Hung, Lee Jong Hun, Lee Sang Hun, Jeong Dae Hong, Jun Bong-Hyun
Division of Science Education, Kangwon National University, Chuncheon, Republic of Korea.
Department of Bioscience and Biotechnology, Konkuk University, Seoul, South Korea.
Adv Exp Med Biol. 2021;1309:41-65. doi: 10.1007/978-981-33-6158-4_3.
Silica consists of one silicon atom and two oxygen atoms (SiO) and is commonly used in various aspects of daily life. For example, it has been used as glass, insulator, and so on. Nowadays, silica is used as core reagents for fabricating and encapsulating nanoparticles (NPs). In this chapter, the usage of silica in nanotechnology is described. Synthesis and surface modification of silica nanoparticles (SiNPs), including via the Stöber method, reverse microemulsion method, and modified sol-gel method, are illustrated. Then, various NPs with silica encapsulation are explained. At last, the biological applications of those mentioned NPs are described.
二氧化硅由一个硅原子和两个氧原子（SiO）组成，常用于日常生活的各个方面。例如，它被用作玻璃、绝缘体等。如今，二氧化硅被用作制造和封装纳米颗粒（NPs）的核心试剂。在本章中，将描述二氧化硅在纳米技术中的用途。阐述了二氧化硅纳米颗粒（SiNPs）的合成和表面改性，包括通过施托伯法、反相微乳液法和改性溶胶 - 凝胶法。然后，解释了各种具有二氧化硅封装的纳米颗粒。最后，描述了上述纳米颗粒的生物学应用。
