Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, Yaoundé, Cameroon.
Division of Cardiology, Department of Medicine, Yaoundé General Hospital, Yaoundé, Cameroon.
J Clin Hypertens (Greenwich). 2021 Jun;23(6):1186-1193. doi: 10.1111/jch.14243. Epub 2021 Mar 29.
The diagnostic accuracy of the electrocardiogram for left ventricular hypertrophy (LVH) is limited. Recently, Peguero and collaborators proposed a novel voltage criterion for its detection with reportedly higher accuracy than the commonly used Cornell and Sokolow-Lyon criteria. While studies done in various populations have confirmed it, there are no available data from black African populations. We conducted a cross-sectional study in a population from Cameroon to compare the Peguero-Lo Presti criterion to the older Cornell, Sokolow-Lyon, and Cornell product criteria, pertaining to their sensitivity, specificity, and area under the receiver operating characteristic curve (AUC), with echocardiography as the reference standard. The study population consisted of 238 participants (54.2% female) with a mean age of 58 (SD 13) years. On echocardiography, the prevalence of LVH was 45.3% (n = 108). The sensitivity was 48.14%, 63.89%, 63.89%, and 67.29% for the Sokolow-Lyon, Peguero-Lo Presti, Cornell, and Cornell product criteria, respectively. The specificity was 73.84%, 75.97%, 79.23%, and 82.31% for the Peguero-Lo Presti, Cornell product, Cornell, and Sokolow-Lyon criteria, respectively. The overall accuracy of the Peguero-Lo Presti (AUC = 0.689) was not significantly different from that of the Cornell (AUC = 0.714), the Cornell product (AUC = 0.717), and the Sokolow-Lyon (AUC = 0.652) (all p ˃ .05). Hypertension and gender influenced the agreement between ECG criteria and echocardiography in the detection of LVH. In conclusion, in this black African population, Peguero-Lo Presti was not significantly more or less accurate than Cornell or Sokolow-Lyon.
心电图诊断左心室肥厚（LVH）的准确性有限。最近，Peguero 及其合作者提出了一种新的电压标准来检测 LVH，据称其准确性高于常用的 Cornell 和 Sokolow-Lyon 标准。虽然在不同人群中的研究已经证实了这一点，但来自非洲黑人人群的数据尚不可用。我们在喀麦隆的一个人群中进行了一项横断面研究，比较了 Peguero-Lo Presti 标准与较老的 Cornell、Sokolow-Lyon 和 Cornell 乘积标准，这些标准的敏感性、特异性和接受者操作特征曲线（ROC）下的面积（AUC），以超声心动图为参考标准。研究人群由 238 名参与者（54.2%为女性）组成，平均年龄为 58（SD 13）岁。在超声心动图上，LVH 的患病率为 45.3%（n=108）。Sokolow-Lyon、Peguero-Lo Presti、Cornell 和 Cornell 乘积标准的敏感性分别为 48.14%、63.89%、63.89%和 67.29%，特异性分别为 73.84%、75.97%、79.23%和 82.31%。Peguero-Lo Presti（AUC=0.689）的总体准确性与 Cornell（AUC=0.714）、Cornell 乘积（AUC=0.717）和 Sokolow-Lyon（AUC=0.652）标准均无显著差异（均 p>.05）。高血压和性别影响心电图标准与超声心动图在 LVH 检测中的一致性。总之，在这个非洲黑人人群中，Peguero-Lo Presti 并不比 Cornell 或 Sokolow-Lyon 更准确或更不准确。
