Gandjian Matthew, Williamson Catherine, Xia Yu, Maturana Carlos, Chervu Nikhil, Verma Arjun, Tran Zachary, Sanaiha Yas, Benharash Peyman
Divisions of Cardiac Surgery, Cardiovascular Outcomes Research Laboratories, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
David Geffen School of Medicine, 155697University of California, Los Angeles, CA, USA.
J Intensive Care Med. 2022 Apr;37(4):535-542. doi: 10.1177/08850666211007062. Epub 2021 Mar 30.
Safety net hospitals (SNH) have been associated with inferior surgical outcomes and increased resource use. Utilization and outcomes for extracorporeal membrane oxygenation (ECMO), a rescue modality for patients with respiratory or cardiac failure, may vary by safety net status. We hypothesized SNH to be associated with inferior outcomes and costs of ECMO in a national cohort.
The 2008-2017 National Inpatient Sample was queried for ECMO hospitalizations and safety net hospitals were identified. Multivariable regression was used to perform risk-adjusted comparisons of mortality, complications and resource utilization at safety net and non-safety net hospitals.
Of 36,491 ECMO hospitalizations, 28.2% were at SNH. On adjusted comparison SNH was associated with increased odds of mortality (AOR: 1.23), tracheostomy use (AOR: 1.51), intracranial hemorrhage (AOR: 1.39), as well as infectious complications (AOR: 1.21, all < .05), with NSNH as reference. SNH was also associated with increased hospitalization duration (β=+4.5 days) and hospitalization costs (β=+$32,880, all < .01).
We have found SNH to be associated with inferior survival, increased complications, and higher costs compared to NSNH. These disparate outcomes warrant further studies examining systemic and hospital-level factors that may impact outcomes and resource use of ECMO at SNH.
安全网医院(SNH)一直与较差的手术结果和资源使用增加有关。体外膜肺氧合(ECMO)是一种用于呼吸或心力衰竭患者的抢救方式,其使用情况和结果可能因安全网状态而异。我们假设在全国队列中,SNH与ECMO较差的结果和成本相关。
查询2008 - 2017年全国住院患者样本中的ECMO住院情况,并确定安全网医院。使用多变量回归对安全网医院和非安全网医院的死亡率、并发症和资源利用进行风险调整后的比较。
在36491例ECMO住院病例中,28.2%发生在SNH。经调整比较,以非安全网医院(NSNH)为参照,SNH与死亡几率增加(调整后比值比[AOR]:1.23)、气管造口术使用(AOR:1.51)、颅内出血(AOR:1.39)以及感染性并发症(AOR:1.21,均P <.05)相关。SNH还与住院时间延长(β = +4.5天)和住院费用增加(β = +32880美元,均P <.01)相关。
我们发现,与NSNH相比,SNH与较差的生存率、更多的并发症和更高的成本相关。这些不同的结果值得进一步研究,以探讨可能影响SNH中ECMO结果和资源使用的系统和医院层面因素。