Chazova L V, Shishova A M, Gromov V L
Research Institute of Preventive Cardiology, USSR Cardiology Research Centre, Moscow.
Cor Vasa. 1988;30(1):11-7.
The effectiveness of preventive measures in populations subjected to a different degree of preventive activity was according to the dynamics of risk factors (RF) tested in the course of four years. Among 6619 examined men aged 40-59 years, a high incidence of RF (79.2%), their connection with ischaemic heart disease (IHD), and frequent simultaneous incidence of several RF even in subjects without IHD were found. The four-year preventive intervention programme was efficient as regards a decline in the incidence of arterial hypertension (AH) from 24.8% to 19.8%, and smoking from 40.1% to 30.6%, simultaneously with a decrease in the mean level of these RF; these favourable changes did not occur in the control group. Data are analysed concerning the percentage of normalization and the incidence of an elevated BP level, cholesterol and body weight. The study proved the possibility of preventively influencing the incidence of AH in the population, and showed the importance of applying preventive measures in subjects with "borderline" values of RF, such as AH and overweight.
根据在四年期间所检测的风险因素（RF）动态变化情况，对处于不同预防活动程度人群中预防措施的有效性进行了研究。在6619名年龄在40至59岁的男性受检者中，发现风险因素的高发生率（79.2%）、它们与缺血性心脏病（IHD）的关联，以及即使在无缺血性心脏病的受试者中也经常出现几种风险因素同时存在的情况。为期四年的预防性干预计划在降低动脉高血压（AH）发病率方面是有效的，从24.8%降至19.8%，吸烟率从40.1%降至30.6%，同时这些风险因素的平均水平也有所下降；而在对照组中未出现这些有利变化。分析了血压水平、胆固醇和体重正常化的百分比以及血压升高的发生率数据。该研究证明了对人群中动脉高血压发病率进行预防性影响的可能性，并表明在具有风险因素“临界”值（如动脉高血压和超重）的受试者中应用预防措施的重要性。
