Cannizzaro L A, Bollum F J, Huebner K, Croce C M, Cheung L C, Xu X, Hecht B K, Hecht F, Chang L M
Genetics and Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Cytogenet Cell Genet. 1988;47(3):121-4. doi: 10.1159/000132527.
We have localized a cDNA fragment that codes for human DNA polymerase-beta. Using somatic cell and in situ hybridization techniques, this cDNA was cloned by screening a human KM-3 cell cDNA library in lambda gt 11 for expression of fused beta-galactosidase-human DNA polymerase-beta proteins. We have mapped this human polymerase-beta gene to the short arm of chromosome 8 in the subregion 8p11----p12.