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[长期新冠:横断面研究]

[Long covid: cross sectional study].

作者信息

Prieto Manuel Antonio, Prieto Omar, Castro Horacio Matias

机构信息

Central de Emergencias de Adultos. Hospital Italiano de San Justo Agustín Rocca, Buenos Aires, Argentina..

Docente de la Universidad de Buenos Aires.

出版信息

Rev Fac Cien Med Univ Nac Cordoba. 2021 Mar 17;78(1):33-36. doi: 10.31053/1853.0605.v78.n1.32048.

Abstract

INTRODUCTION

Coronavirus disease 2019 (COVID-19) is a public health problem worldwide. After 3 weeks of the onset of the disease, between 10-87% of patients persist with symptoms. The objective of the study was to evaluate the persistence of symptoms in patients with COVID-19, the associated factors, and to explore the patients' perception of the disease.

MATERIALS AND METHODS

We conducted a cross-sectional study that included 85 patients with a confirmed diagnosis of COVID-19, who attended on an outpatient basis after the acute phase (> 3 weeks) of the disease.

RESULTS

The median time from diagnosis to outpatient consultation was 53 days (interquartile range 31-65). Most (86%) had mild disease, 45% were women and the mean age was 43 years (standard deviation of 13). After the acute phase of the disease 52% (95% CI 41-63%) of the patients persisted with symptoms. The most frequently persistent symptoms were fatigue (49%) and cough (33%). Nineteen percent had insomnia and sixteen percent had anxiety. Female sex, obesity, age between 35-55 years, and initial hospitalization were associated with the persistence of symptoms. Twenty percent of the patients stopped following the prevention recommendations because they believed they were immunized.

CONCLUSION

More than half of the patients persisted with symptoms 3 weeks after the COVID-19 diagnosis, so medical follow-up is important. Female sex, obesity, age 35-55 years, and initial hospitalization were associated factors. The symptoms usually resolved over time.

摘要

引言

2019冠状病毒病(COVID-19)是一个全球性的公共卫生问题。在疾病发作3周后,10%-87%的患者仍有症状。本研究的目的是评估COVID-19患者症状的持续情况、相关因素,并探讨患者对该疾病的认知。

材料与方法

我们进行了一项横断面研究,纳入了85例确诊为COVID-19的患者,这些患者在疾病急性期(>3周)后门诊就诊。

结果

从诊断到门诊咨询的中位时间为53天(四分位间距31-65天)。大多数(86%)患者病情较轻,45%为女性,平均年龄为43岁(标准差13)。在疾病急性期后,52%(95%可信区间41%-63%)的患者仍有症状。最常见的持续症状是疲劳(49%)和咳嗽(33%)。19%的患者有失眠,16%的患者有焦虑。女性、肥胖、35-55岁年龄以及最初住院与症状持续有关。20%的患者不再遵循预防建议,因为他们认为自己已获得免疫。

结论

超过一半的患者在COVID-19诊断3周后仍有症状,因此医学随访很重要。女性、肥胖、35-55岁年龄以及最初住院是相关因素。症状通常会随时间缓解。

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