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新冠长期症状患者的肌肉骨骼症状:一项针对伊朗患者的横断面研究。

Musculoskeletal symptoms in patients with long COVID: A cross-sectional study on Iranian patients.

作者信息

Azadvari Mohaddeseh, Haghparast Afarin, Nakhostin-Ansari Amin, Emami Razavi Seyede Zahra, Hosseini Maryam

机构信息

Department of Physical Medicine and Rehabilitation, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Department of Physical Medicine and Rehabilitation, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Heliyon. 2022 Aug;8(8):e10148. doi: 10.1016/j.heliyon.2022.e10148. Epub 2022 Aug 11.

Abstract

BACKGROUND AND OBJECTIVES

Latest studies have revealed that an increasing number of Corona Virus Disease of 2019 (COVID-19) patients may continue to feel symptoms after the acute phase. This study aimed to evaluate the prevalence of musculoskeletal symptoms after the acute phase of COVID-19 and its associated factors.

METHODS

We designed a cross-sectional study from January 2021 to April 2021. An online questionnaire was designed and sent to patients who had recovered from COVID-19. The questionnaire contained questions on participants' demographic characteristics, COVID-19 course at its acute phase, and musculoskeletal symptoms after recovering from COVID-19. Musculoskeletal symptoms associations with patients' characteristic and COVID-19 course was evaluated.

RESULT

239 patients, including 72 (30.1%) males and 167 (69.9%) females with a mean age of 37.96 years (SD = 11.19), were included in the study. 98.74% of our patients had experienced at least one musculoskeletal symptom after recovering from COVID-19, and the most common symptom was fatigue, as 91.2% of participants experienced this symptom, followed by myalgia, headache, and low back pain. High BMI, hospitalization, and ICU admission were associated with a higher risk of musculoskeletal symptoms.

CONCLUSION

This study indicated a high prevalence of persistent musculoskeletal symptoms among patients who recovered from COVID-19. Modifiable factors, such as BMI, can be targeted to reduce the prevalence of musculoskeletal symptoms in COVID-19 survivors and reduce its burden.

摘要

背景与目的

最新研究表明,越来越多的2019冠状病毒病(COVID-19)患者在急性期后可能仍会感到症状。本研究旨在评估COVID-19急性期后肌肉骨骼症状的患病率及其相关因素。

方法

我们设计了一项从2021年1月至2021年4月的横断面研究。设计了一份在线问卷并发送给从COVID-19中康复的患者。问卷包含有关参与者的人口统计学特征、COVID-19急性期病程以及从COVID-19康复后的肌肉骨骼症状的问题。评估了肌肉骨骼症状与患者特征和COVID-19病程的关联。

结果

本研究纳入了239名患者,其中男性72名(30.1%),女性167名(69.9%),平均年龄为37.96岁(标准差=11.19)。98.74%的患者在从COVID-19康复后至少经历过一种肌肉骨骼症状,最常见的症状是疲劳,91.2%的参与者有此症状,其次是肌痛、头痛和腰痛。高体重指数、住院和入住重症监护病房与肌肉骨骼症状的较高风险相关。

结论

本研究表明,从COVID-19康复的患者中持续性肌肉骨骼症状的患病率较高。可以针对体重指数等可改变的因素来降低COVID-19幸存者中肌肉骨骼症状的患病率并减轻其负担。

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