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增加肉类消费与降低结核病治疗失败率相关:一项队列研究。

Increased meat consumption is associated with reduced tuberculosis treatment failure rate: A cohort study.

机构信息

Institute of Nutrition and Health, School of Public Health, Qingdao University, Qingdao, Shandong, People's Republic of China.

Department of Respiratory Medicine, Linyi People's Hospital East Branch, Linyi, China.

出版信息

Asia Pac J Clin Nutr. 2021;30(1):122-129. doi: 10.6133/apjcn.202103_30(1).0015.

DOI:10.6133/apjcn.202103_30(1).0015
PMID:33787048
Abstract

BACKGROUND AND OBJECTIVES

Information regarding the relationship between dietary meat intake and tuberculosis treatment outcomes among patients with tuberculosis is still limited. The aim of the present study was to investigate the relationship between meat consumption and tuberculosis treatment outcomes in patients with pulmonary tuberculosis.

METHODS AND STUDY DESIGN

A pulmonary tuberculosis cohort study including 2,261 patients with pulmonary tuberculosis was conducted in Linyi, Shandong Province, China from 2009 to 2013. Dietary data were collected using a semi-quantitative food frequency questionnaire. Treatment outcomes were assessed using a combination of sputum smear microscopy and chest computerized tomography.

RESULTS

In a multiple adjusted model, the higher quartile of total meat (OR=0.59, 95% CI, 0.38-0.91) was associated with a decreased failure rate of pulmonary tuberculosis treatment. In addition, higher consumption of chicken (OR=0.62; 95% CI, 0.44-0.87) and pork (OR=0.54; 95% CI, 0.31-0.95) was associated with a lower failure rate of tuberculosis treatment.

CONCLUSIONS

Increased dietary intake of total meat, pork, and chicken are associated with a decreased failure rate of pulmonary tuberculosis treatment. A higher dietary meat intake may be beneficial in pulmonary tuberculosis treatment.

摘要

背景和目的

关于饮食中肉类摄入量与结核病患者治疗结果之间关系的信息仍然有限。本研究旨在调查肺结核患者中肉类消费与结核病治疗结果之间的关系。

方法和研究设计

在中国山东省临沂市,进行了一项包含 2261 例肺结核患者的肺结核队列研究。采用半定量食物频率问卷收集饮食数据。采用痰涂片显微镜检查和胸部计算机断层扫描相结合的方法评估治疗结果。

结果

在多因素调整模型中,总肉类摄入量较高的四分位数与肺结核治疗失败率降低相关(OR=0.59,95%CI,0.38-0.91)。此外,鸡肉(OR=0.62;95%CI,0.44-0.87)和猪肉(OR=0.54;95%CI,0.31-0.95)摄入量较高与结核病治疗失败率降低相关。

结论

增加总肉类、猪肉和鸡肉的饮食摄入与降低肺结核治疗失败率有关。较高的饮食肉类摄入量可能对肺结核治疗有益。

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