Affifiliated Hospital of Jiangxi University of Traditional Chinese Medicine.
Jiangxi University of Traditional Chinese Medicine, Nanchang.
Medicine (Baltimore). 2021 Apr 2;100(13):e25312. doi: 10.1097/MD.0000000000025312.
Plaque psoriasis (PSO) is a common clinical chronic inflammatory skin disease. The incidence rate is increasing year by year due to the fast pace of work and unhealthy diet. Fire needle has been widely used in the treatment of PSO. However, the efficacy of fire needle for PSO is uncertain. Thus, the purpose of this systematic review is to evaluate the effectiveness and safety of fire needle for PSO (blood stasis syndrome).
The following electronic databases will be searched from inception to October 2020:PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Infrastructure, WangFang Database, Chinese Science Journal Database, Chinese Biomedical Literature Database. In addition, other documents that meet the requirements will be manually searched, including conference papers, dissertations, etc. All randomized controlled trials using fire needle to treat PSO (blood stasis syndrome) that meet the criteria for inclusion will be included. The primary outcomes are clinical efficacy, Psoriasis area and severity index. Secondary outcomes include Itchy, TCM evaluation standard syndrome score, Dermatological quality of life index, and adverse events. To complete data synthesis and assess the risk of bias, we will use the RevMan V.5.3 software.
The review results will be published in a peer-reviewed journal.
This study will provide high-quality evidence based medicine to evaluate the effectiveness and safety of fire needle for PSO (blood stasis syndrome), and further seek its scientific and effective chinese medicine treatment methods.
INPLASY202120007.
斑块状银屑病（PSO）是一种常见的临床慢性炎症性皮肤病。由于工作节奏快、饮食不健康，其发病率呈逐年上升趋势。火针已广泛应用于 PSO 的治疗。然而，火针对 PSO（血瘀证）的疗效尚不确定。因此，本系统评价的目的是评估火针对 PSO（血瘀证）的有效性和安全性。
我们将从建库至 2020 年 10 月检索以下电子数据库：PubMed、Web of Science、Embase、Cochrane 图书馆、中国知网、万方数据库、中国科学引文数据库、中国生物医学文献数据库。此外，还将手工检索其他符合要求的文献，包括会议论文、学位论文等。所有符合纳入标准的用火针治疗 PSO（血瘀证）的随机对照试验都将被纳入。主要结局指标是临床疗效、银屑病面积和严重程度指数。次要结局指标包括瘙痒、中医证候评价标准评分、皮肤病生活质量指数和不良事件。为了完成数据综合和评估偏倚风险，我们将使用 RevMan V.5.3 软件。
综述结果将发表在同行评议的期刊上。
本研究将提供高质量的循证医学证据，评估火针对 PSO（血瘀证）的有效性和安全性，并进一步寻找其科学有效的中医药治疗方法。
INPLASY 注册号：INPLASY202120007。
