Jinhua Fifth Hospital, Jinhua, China.
Department of First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Medicine (Baltimore). 2024 Feb 16;103(7):e35832. doi: 10.1097/MD.0000000000035832.
The mechanism of action of fire acupuncture and Chinese medicine in psoriasis is unclear. In this paper, the efficacy of the 2 therapies was compared through a comprehensive analysis of their recurrence rates for clinical reference.
In this meta-analysis, we searched PubMed, Embase, Cochrane Library, CNKI, Wanfang, CQVIP, and CBM data from the establishment of the databases to May 2023. The study proposed to use randomized controlled trial research methods, excluding published literature, unpublished literature, literature with incomplete or inadequate information, animal experiments, literature reviews and systematic studies. Data were processed using STATA 15.1 software.
Our group previous study found that the clinical efficacy of the fire-acupuncture group was significantly improved compared to that of Chinese herbal medicine alone (RR = 1.20, 95% CI: 1.13-1.27). Also, there were significant reductions in Psoriasis Area and Severity Index (PASI) score (SMD = -1.04,95% CI: -1.48 to -0.60), area of skin damage (SMD = -0.40,95% CI: -0.75 to -0.04), and pruritus (SMD = -1.04,95% CI: -1.32 to -0.76). Our previous study found that Dermatology Life Quality Index (DLQI) was significantly lower in the fire acupuncture group compared to herbal medicine alone (SMD = -1.61,95% CI: -3.08 to -0.15). The combined analysis found that the recurrence rate was significantly lower in the fire-acupuncture group compared to herbal medicine alone (RR = 0.21,95% CI:0.07-0.60).
Fire needle can improve the efficacy of TCM in the treatment of psoriasis, including the area, severity and itching of skin lesions, and reduce the recurrence rate, which is worthy of clinical promotion.
火针和中医药治疗银屑病的作用机制尚不清楚。本文通过对其复发率的综合分析,比较了两种疗法的疗效,为临床提供参考。
本荟萃分析检索了 PubMed、Embase、Cochrane 图书馆、中国知网、万方、维普和 CBM 数据库自建库至 2023 年 5 月的相关文献,提出采用随机对照试验研究方法,排除发表文献、未发表文献、信息不全或不充分的文献、动物实验、文献综述和系统研究。采用 STATA 15.1 软件进行数据处理。
本研究前期发现火针组临床疗效优于中药组(RR=1.20,95%CI:1.131.27),且 PASI 评分(SMD=-1.04,95%CI:-1.48-0.60)、皮损面积(SMD=-0.40,95%CI:-0.75-0.04)、瘙痒程度(SMD=-1.04,95%CI:-1.32-0.76)均明显降低,且前期发现火针组患者 DLQI 评分(SMD=-1.61,95%CI:-3.08-0.15)低于中药组。联合分析发现火针组复发率低于中药组(RR=0.21,95%CI:0.070.60)。
火针能提高中医药治疗银屑病的疗效,包括皮损面积、严重程度和瘙痒程度,降低复发率,值得临床推广。