Ophthalmology Department, Çam and Sakura City Hospital, Başakşehir Olimpiyat Bulvarı Yolu, 34480, Başakşehir, İstanbul, Turkey.
Radiology Department, Bakirkoy Dr Sadi Konuk Training and Research Hospital, Bakirkoy, İstanbul, Turkey.
Neurol Sci. 2021 Dec;42(12):5165-5170. doi: 10.1007/s10072-021-05208-z. Epub 2021 Mar 31.
The objective of this study was to investigate the optic nerve's elastic properties and optic nerve sheath diameter (ONSD) using shear-wave elastography (SWE) in patients with idiopathic intracranial hypertension (IIH) compared to healthy individuals.
The study included 22 IIH patients and 15 healthy subjects. SWEs were performed on the optic nerve and ONSD, and optic nerve stiffness were measured.
The patients with IIH demonstrated higher stiffness of the optic nerve compared with that of healthy volunteers (P < 0.001). The optic nerve sheath diameter of the optic nerve in the IIH group was significantly larger than that in the control group (P < 0.001). There was no correlation between the disease duration and SWE values in the Spearman correlation test.
These findings suggest that ONSD can be used as a follow-up method in the treatment of IIH. However, there was not any correlation between the disease duration and SWE-based stiffness measurement of the optic nerve.
本研究旨在通过剪切波弹性成像（SWE）比较特发性颅内高压（IIH）患者与健康个体，研究视神经的弹性特性和视神经鞘直径（ONSD）。
本研究纳入了 22 例 IIH 患者和 15 名健康受试者。对视神经和 ONSD 进行 SWE 检查，并测量视神经硬度。
与健康志愿者相比，IIH 患者的视神经硬度更高（P<0.001）。IIH 组的视神经鞘直径明显大于对照组（P<0.001）。Spearman 相关检验显示，疾病持续时间与 SWE 值之间无相关性。
这些发现表明，ONSD 可作为 IIH 治疗的随访方法。但是，视神经 SWE 硬度测量与疾病持续时间之间没有相关性。
