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假设抗坏血酸锌作为提高针对 COVID-19 的抗病毒抗性的最佳锌离子载体。

Hypothesis of zinc ascorbate as best zinc ionophore for raising antiviral resistance against Covid-19.

机构信息

Recanati, Italy.

出版信息

J Med Virol. 2021 Sep;93(9):5205-5208. doi: 10.1002/jmv.26989. Epub 2021 May 28.

Abstract

Zinc ascorbate could prevent and treat Covid‐19 by raising antiviral resistance to SARS‐CoV‐2 virus via increase of intracellular zinc concentration as a zinc ionophore more than other salts of zinc or zinc with vitamin C. Tests in vitro and clinical trials for Covid‐19 prevention and treatment with zinc ascorbate are strongly recommended and should start as soon as possible. Potential advantages of zinc ascorbate supplementation over vaccines and drugs are also discussed, with supplementation suggestions.

摘要

抗坏血酸锌通过增加细胞内锌浓度作为锌载体,比其他锌盐或锌与维生素 C 更能提高抗病毒对 SARS-CoV-2 病毒的抵抗力,从而可以预防和治疗 Covid-19。强烈建议对锌抗坏血酸进行体外测试和临床试验,以预防和治疗 Covid-19,并且应尽快开始。还讨论了锌抗坏血酸补充剂相对于疫苗和药物的潜在优势,并提出了补充建议。

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本文引用的文献

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Vitamin D Status in Hospitalized Patients with SARS-CoV-2 Infection.住院的 SARS-CoV-2 感染患者的维生素 D 状况。
J Clin Endocrinol Metab. 2021 Mar 8;106(3):e1343-e1353. doi: 10.1210/clinem/dgaa733.
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Structure of the RNA-dependent RNA polymerase from COVID-19 virus.COVID-19 病毒的依赖 RNA 的 RNA 聚合酶的结构。
Science. 2020 May 15;368(6492):779-782. doi: 10.1126/science.abb7498. Epub 2020 Apr 10.
7
Zinc-chelated Vitamin C Stimulates Adipogenesis of 3T3-L1 Cells.锌螯合维生素C刺激3T3-L1细胞的脂肪生成。
Asian-Australas J Anim Sci. 2013 Aug;26(8):1189-96. doi: 10.5713/ajas.2013.13179.
10
A glass of water immediately increases gastric pH in healthy subjects.一杯水会立即提高健康受试者的胃内pH值。
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