Zhang Lei, Wang Ya-Ling, Lou Ji-Chang, Xia Guo-Jie, Xu Bo, Feng Shou-Han, Guan Xin-Jun
Huzhou Hospital of TCM, Affiliated to Zhejiang Chinese Medical University, Huzhou 313000, China.
Tongzi Hospital of TCM.
Zhongguo Zhen Jiu. 2020 Nov 12;40(11):1164-8. doi: 10.13703/j.0255-2930.20191119-k0005.
To observe the effect of ginger-partitioned moxibustion on digestive tract reaction, quality of life and white blood cell count after chemotherapy in advanced malignant bone tumors patients.
A total of 64 patients were randomly divided into an observation group and a control group, 32 cases in each group. Both groups were treated with adriamycin combined with cisplatin (AP) chemotherapy. The patients in the control group were treated by tropisetron hydrochloride intravenous on preventing the vomiting 1 h before receiving chemotherapy. On the basis of the control group, the patients in the observation group were treated with ginger-partitioned moxibustion at Neiguan (PC 6), Zusanli (ST 36), Shenque (CV 8), and Zhongwan (CV 12) 2 h after chemotherapy, once a day, 30 min each time. The course of chemotherapy, ginger-partitioned moxibustion and tropisetron hydrochloride intravenous was 5 days. The digestive tract reaction rating, quality of life score and white blood cell count were compared 1 d before chemotherapy, 2 d after chemotherapy and 7 d after chemotherapy between the two groups.
The number of 0 grade in digestive tract reaction 2 d and 7 d after chemotherapy in the observation group was significantly higher than that in the control group (<0.05), and the number of Ⅲ、Ⅳ grade was lower than that in the control group (<0.05). The quality of life scores of both groups 2 d after chemotherapy were lower than those before chemotherapy (<0.05), and there was no significant difference between the two groups (>0.05). The quality of life score of the control group 7 d after chemotherapy was lower than that before chemotherapy (<0.05), the quality of life score of the observation group was not statistically different from that before chemotherapy (>0.05), and the quality of life score in the observation group was higher than that in the control group (<0.05). The white blood cell count 2 d after chemotherapy in both groups was lower than before treatment (<0.05), and there was no significant difference between the two groups (>0.05). Seven days after chemotherapy, the white blood cell count in the control group was lower than that before chemotherapy (<0.05), while there was no significant difference in the observation group compared with before chemotherapy (>0.05), and the white blood cell count in the observation group was higher than that in the control group (<0.05).
Ginger-partitioned moxibustion can prevent and treat vomiting after chemotherapy in advanced malignant bone tumors, and improve the quality of life and white blood cell count of patients.
观察隔姜灸对晚期恶性骨肿瘤患者化疗后消化道反应、生活质量及白细胞计数的影响。
将64例患者随机分为观察组和对照组，每组32例。两组均采用阿霉素联合顺铂（AP）化疗。对照组患者在化疗前1小时静脉滴注盐酸托烷司琼预防呕吐。观察组患者在对照组基础上，于化疗后2小时采用隔姜灸内关（PC 6）、足三里（ST 36）、神阙（CV 8）、中脘（CV 12），每日1次，每次30分钟。化疗、隔姜灸及盐酸托烷司琼静脉滴注疗程均为5天。比较两组化疗前1天、化疗后2天及化疗后7天的消化道反应分级、生活质量评分及白细胞计数。
观察组化疗后2天及7天消化道反应0级例数显著高于对照组（<0.05），Ⅲ、Ⅳ级例数低于对照组（<0.05）。两组化疗后2天生活质量评分均低于化疗前（<0.05），两组间比较差异无统计学意义（>0.05）。对照组化疗后7天生活质量评分低于化疗前（<0.05），观察组化疗后7天生活质量评分与化疗前比较差异无统计学意义（>0.05），且观察组生活质量评分高于对照组（<0.05）。两组化疗后2天白细胞计数均低于治疗前（<0.05），两组间比较差异无统计学意义（>0.05）。化疗后7天，对照组白细胞计数低于化疗前（<0.05），观察组与化疗前比较差异无统计学意义（>0.05），且观察组白细胞计数高于对照组（<0.05）。
隔姜灸可防治晚期恶性骨肿瘤患者化疗后呕吐，提高患者生活质量及白细胞计数。
