Department of Chemistry, College of Chemistry and Chemical Engineering, Ministry of Education (MOE) Key Laboratory of Spectrochemical Analysis and Instrumentation, and Collaborative Innovation Center of Chemistry for Energy Materials, Xiamen University, Xiamen 361005, China.
Institute of Pharmacology and Toxicology, Beijing 100027, China.
Inorg Chem. 2021 Apr 19;60(8):5413-5418. doi: 10.1021/acs.inorgchem.1c00104. Epub 2021 Mar 31.
We report a new scheme for chiral recognition using coordination polymers of Ag with a chiral thiol ligand that contains a binding group. -Benzoyl-l-cysteine ethyl ester equipped with a boronic acid group at the para position of the phenyl ring forms coordination polymers with Ag in alkaline aqueous solutions that exhibit excellent selectivity toward a d-glucose enantiomer over l-glucose, while the coordination polymers from the d-cysteine-based thiol ligand are specific for l-glucose. It is assumed that a conformation change occurs upon interaction of a saccharide molecule with the polymeric chain receptor, for which the next binding is promoted, leading to the highly effective chiral recognition, despite the flexible nature of the polymeric receptor.
我们报告了一种使用含有结合基团的手性硫醇配体的 Ag 配位聚合物进行手性识别的新方案。-苯甲酰基-l-半胱氨酸乙酯在苯环的对位带有硼酸基团，在碱性水溶液中与 Ag 形成配位聚合物，对 d-葡萄糖对映体表现出优异的选择性，而基于 d-半胱氨酸的硫醇配体的配位聚合物则对 l-葡萄糖具有特异性。据推测，在糖分子与聚合物链受体相互作用时会发生构象变化，这促进了下一次结合，从而导致高度有效的手性识别，尽管聚合物受体具有柔性。
