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脊髓刺激术成功应用于难治性上肢疼痛:病例系列报道

Successful application of burst spinal cord stimulation for refractory upper limb pain: a case series.

作者信息

Lee Kuen Su, Jang Yoo Kyung, Park Gene Hyun, Jun In Jae, Koh Jae Chul

机构信息

Department of Anaesthesiology and Pain Medicine, Eulji University Uijeongbu Eulji Medical Centre, Uijeongbu, Republic of Korea.

Department of Anaesthesiology and Pain Medicine, Korea University Anam Hospital, Seoul, Republic of Korea.

出版信息

J Int Med Res. 2021 Mar;49(3):3000605211004035. doi: 10.1177/03000605211004035.

DOI:10.1177/03000605211004035
PMID:33788644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8020113/
Abstract

Spinal cord stimulation (SCS) has been used to treat sustained pain that is intractable despite various types of treatment. However, conventional tonic waveform SCS has not shown promising outcomes for spinal cord injury (SCI) or postamputation pain. The pain signal mechanisms of burst waveforms are different to those of conventional tonic waveforms, but few reports have presented the therapeutic potential of burst waveforms for the abovementioned indications. This current case report describes two patients with refractory upper limb pain after SCI and upper limb amputation that were treated with burst waveform SCS. While the patients could not obtain sufficient therapeutic effect with conventional tonic waveforms, the burst waveforms provided better pain reduction with less discomfort. However, further studies are necessary to better clarify the mechanisms and efficacy of burst waveform SCS in patients with intractable pain.

摘要

脊髓刺激(SCS)已被用于治疗尽管经过各种类型的治疗但仍难以治愈的持续性疼痛。然而,传统的强直波形SCS在脊髓损伤(SCI)或截肢后疼痛方面并未显示出有前景的结果。爆发波形的疼痛信号机制与传统的强直波形不同,但很少有报告阐述爆发波形在上述适应症中的治疗潜力。本病例报告描述了两名SCI和上肢截肢后难治性上肢疼痛的患者,他们接受了爆发波形SCS治疗。虽然患者使用传统的强直波形无法获得足够的治疗效果,但爆发波形在减轻疼痛的同时减少了不适感。然而,需要进一步研究以更好地阐明爆发波形SCS在难治性疼痛患者中的机制和疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/81a9478a8f5b/10.1177_03000605211004035-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/7eb2cbc2c263/10.1177_03000605211004035-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/e403f4fd145a/10.1177_03000605211004035-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/136fc6887c1a/10.1177_03000605211004035-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/5ec6d4f06a8b/10.1177_03000605211004035-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/81a9478a8f5b/10.1177_03000605211004035-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/7eb2cbc2c263/10.1177_03000605211004035-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/e403f4fd145a/10.1177_03000605211004035-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/136fc6887c1a/10.1177_03000605211004035-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/5ec6d4f06a8b/10.1177_03000605211004035-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e05c/8020113/81a9478a8f5b/10.1177_03000605211004035-fig5.jpg

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J Pain Res. 2020 Nov 10;13:2837-2851. doi: 10.2147/JPR.S278661. eCollection 2020.
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Spinal cord stimulation in chronic pain: technical advances.慢性疼痛中的脊髓刺激:技术进展
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Sustained Long-Term Outcomes With Closed-Loop Spinal Cord Stimulation: 12-Month Results of the Prospective, Multicenter, Open-Label Avalon Study.
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Neurosurgery. 2020 Sep 15;87(4):E485-E495. doi: 10.1093/neuros/nyaa003.
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Current Evidence Lacking to Guide Clinical Practice for Spinal Cord Stimulation in the Treatment of Neuropathic Pain in Spinal Cord Injury: A Review of the Literature and a Proposal for Future Study.目前缺乏指导脊髓刺激治疗脊髓损伤神经性疼痛的临床实践的证据:文献回顾与未来研究建议。
Pain Pract. 2020 Mar;20(3):325-335. doi: 10.1111/papr.12855. Epub 2020 Feb 10.
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