Cardiovascular Department, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Department of Cardiology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, People's Republic of China.
Sci Prog. 2021 Jan-Mar;104(1):368504211003762. doi: 10.1177/00368504211003762.
China is at a stage of rapid urbanization over the past decades, and the association of urbanization with cardiovascular disease has been confirmed by previous studies. However, few studies assessed the association of urbanization with cardiovascular risk factors, especially in Chinese population. We conducted a cross-sectional, populational-based study, using data from China Health and Nutrition Survey (CHNS) in 2009. The logistic regression was used to assess the association of urbanization measured by urban index with cardiovascular risk factors (diabetes mellitus, hypertension, dyslipidemia, obesity, smoking, physical activity and fruits and vegetables consumption), varied with sex. The current study included 18,887 participants enrolled (mean age 39.8 ± 19.8 years; 52.2% female) who live in China. In regression model, the urban index was significantly associated with the variations of cardiovascular risk factors for male, including diabetes (OR 1.34, 95% CI: 1.22-1.48), hypercholesterolemia (OR 1.15, 95% CI: 1.09-1.22), never smoking (OR 0.92, 95% CI: 0.89-0.96), higher fruits and vegetables consumptions (OR 0.93, 95% CI: 0.87-0.99), higher body mass index (BMI) (OR 1.16, 95% CI: 1.10-1.22), and higher physical activity (OR 0.69, 95% CI: 0.66-0.73). Compared with the male, the associations of urban index with cardiovascular risk factors for female were similar, but not for BMI (OR 1.00, 95% CI: 0.96-1.05). The present finding emphasizes the changes of cardiovascular risk factors associated with urbanization in China, and indicated that close attention should be paid to the risk of hypercholesterolemia, diabetes and men's obesity in the process of urbanization.
中国在过去几十年经历了快速的城市化进程,先前的研究已经证实城市化与心血管疾病之间存在关联。然而,很少有研究评估城市化与心血管危险因素之间的关联,特别是在中国人群中。我们进行了一项横断面、基于人群的研究,使用了 2009 年中国健康与营养调查(CHNS)的数据。使用逻辑回归评估了城市化指数与心血管危险因素(糖尿病、高血压、血脂异常、肥胖、吸烟、体力活动和水果与蔬菜摄入)之间的关联,关联程度因性别而异。本研究共纳入 18887 名参与者(平均年龄 39.8±19.8 岁,52.2%为女性),他们居住在中国。在回归模型中,城市化指数与男性心血管危险因素的变化显著相关,包括糖尿病(OR 1.34,95%CI:1.22-1.48)、高胆固醇血症(OR 1.15,95%CI:1.09-1.22)、从不吸烟(OR 0.92,95%CI:0.89-0.96)、较高的水果和蔬菜摄入量(OR 0.93,95%CI:0.87-0.99)、较高的体重指数(OR 1.16,95%CI:1.10-1.22)和较高的体力活动水平(OR 0.69,95%CI:0.66-0.73)。与男性相比,城市化指数与女性心血管危险因素的关联相似,但与 BMI 无关(OR 1.00,95%CI:0.96-1.05)。本研究结果强调了中国城市化与心血管危险因素变化之间的关系,提示在城市化进程中应密切关注高胆固醇血症、糖尿病和男性肥胖的风险。