Westergaard J M, Kramer T T
Appl Environ Microbiol. 1977 Nov;34(5):506-11. doi: 10.1128/aem.34.5.506-511.1977.
Bdellovibrio strain MS7 force-fed to fish and frogs via an intragastric tube did not become an integral component of the intestinal microflora. Strain MS7 fed to mice in drinking water was not recovered from the intestinal tract of mice. However, in vitro, the organism multiplied in intestinal contents of frogs and mice. Bdellovibrio inoculated into rabbit ileal loops was greatly reduced in number within 24 h. It was concluded that strains MS7 could be considered nonpathogenic to animals, at least when introduced into the digestive tract, and that it is not feasible at the present time to lyse pathogenic, gram-negative bacteria in the alimentary tract with Bdellovibrio.
通过胃管将蛭弧菌MS7株强行投喂给鱼和青蛙后，它并未成为肠道微生物群的一个组成部分。将MS7株通过饮水投喂给小鼠后，在小鼠肠道中未检测到该菌株。然而，在体外，该菌能在青蛙和小鼠的肠道内容物中繁殖。接种到兔回肠袢中的蛭弧菌在24小时内数量大幅减少。得出的结论是，至少当引入消化道时，MS7株可被认为对动物无致病性，并且目前利用蛭弧菌裂解消化道中的致病性革兰氏阴性菌是不可行的。
