The Physiological TMPRSS2 Inhibitor HAI-2 Alleviates SARS-CoV-2 Infection.
作者信息
Tomita Yuriko, Matsuyama Shutoku, Fukuhara Hideo, Maenaka Katsumi, Kataoka Hiroaki, Hashiguchi Takao, Takeda Makoto
机构信息
Department of Virology 3, National Institute of Infectious Diseases, Tokyo, Japan.
Laboratory of Biomolecular Science and Center for Research and Education on Drug Discovery, Faculty of Pharmaceutical Sciences, Hokkaido University, Hokkaido, Japan.
出版信息
J Virol. 2021 May 24;95(12). doi: 10.1128/JVI.00434-21.
Abstract
摘要
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本文引用的文献
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J Biol Chem. 2021 Jan-Jun;296:100135. doi: 10.1074/jbc.REV120.015980. Epub 2020 Dec 6.
2
Inhibition of TMPRSS2 by HAI-2 reduces prostate cancer cell invasion and metastasis.抑制 TMPRSS2 表达可降低前列腺癌细胞侵袭和转移。
Oncogene. 2020 Sep;39(37):5950-5963. doi: 10.1038/s41388-020-01413-w. Epub 2020 Aug 10.
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Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections.无症状 SARS-CoV-2 感染的临床和免疫学评估。
Nat Med. 2020 Aug;26(8):1200-1204. doi: 10.1038/s41591-020-0965-6. Epub 2020 Jun 18.
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Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV.SARS-CoV-2 刺突糖蛋白的特征及其对病毒进入的影响，以及与 SARS-CoV 的免疫交叉反应性。
Nat Commun. 2020 Mar 27;11(1):1620. doi: 10.1038/s41467-020-15562-9.
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