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尼泊尔加德满都山谷地区结核病患者中的糖尿病患病率。

Prevalence of Diabetes in Tuberculosis Patients in Kathmandu Valley, Nepal.

机构信息

National Center for Global Health and Medicine, Japan.

Department of Microbiology, Osaka Medical Collage, Japan.

出版信息

Jpn J Infect Dis. 2021 Nov 22;74(6):507-510. doi: 10.7883/yoken.JJID.2019.375. Epub 2021 Mar 31.

Abstract

In this descriptive cross-sectional study, the data on the prevalence of diabetes mellitus (DM) among tuberculosis (TB) patients at the Urban Directly Observed Treatment Centers in the Kathmandu, Bhaktapur, and Lalitpur districts of Nepal were collected. The prevalence of DM was assessed in 67 previously treated TB (PTTB) and 214 new TB patients. DM was diagnosed in 8 PTTB and 20 new TB patients. Clinical interviews identified 14 patients with DM, rapid blood glucose test was used to diagnose DM in 4 patients, and oral glucose tolerance test was used to diagnose DM in another 4 patients. Impaired glucose tolerance and impaired fasting glycemia were observed in 8 and 5 patients, respectively. The 18-24-year age group had the largest number of new TB patients (82, 38.3%). However, the incidence of DM among TB patients was higher in the >35-year age group. Moreover, DM was diagnosed in 24.2% of PTTB patients and in 23.1% of new TB patients. To determine the impact of DM screening in TB patients, a larger number of samples should be analyzed. DM screening for patients with TB is expected to start in developing countries. This should be initiated by conducting clinical interviews about DM and glucose tests using rapid kits.

摘要

在这项描述性的横断面研究中,收集了尼泊尔加德满都、巴克塔普尔和勒利德布尔地区城市直接观察治疗中心的结核病 (TB) 患者中糖尿病 (DM) 患病率的数据。评估了 67 例既往治疗过的结核病 (PTTB) 和 214 例新结核病患者的 DM 患病率。8 例 PTTB 和 20 例新结核病患者被诊断为 DM。临床访谈确定了 14 例 DM 患者,4 例患者使用快速血糖检测诊断 DM,4 例患者使用口服葡萄糖耐量试验诊断 DM。8 例患者存在糖耐量受损,5 例患者存在空腹血糖受损。18-24 岁年龄组新结核病患者数量最多(82 例,38.3%)。然而,TB 患者中 DM 的发病率在>35 岁年龄组更高。此外,24.2%的 PTTB 患者和 23.1%的新结核病患者被诊断为 DM。为了确定在结核病患者中进行 DM 筛查的影响,应该分析更多的样本。预计 DM 筛查将在发展中国家开始对结核病患者进行。这可以通过进行有关 DM 的临床访谈和使用快速试剂盒进行葡萄糖检测来启动。

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