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原发性印戒细胞宫颈癌罕见病例:早期伴独立双侧卵巢转移

A Rare Case of Primary Signet-Ring Cell Cervical Carcinoma: Early Stage with Independent Bilateral Ovarian Metastases.

作者信息

Li Shiyun, Gan Fuqiang, Luo Manling, Luo Puying

机构信息

Department of Gynecology, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, People's Republic of China.

出版信息

Onco Targets Ther. 2021 Mar 23;14:2101-2107. doi: 10.2147/OTT.S300424. eCollection 2021.

Abstract

BACKGROUND

Primary signet-ring cell carcinoma of the uterine cervix (PSRCCC) is defined as a mucinous carcinoma. PSRCCC with independent bilateral ovarian metastases has not been previously reported in the literature.

CASE PRESENTATION

Herein we describe a case of PSRCCC with ovarian involvement. The patient underwent a detailed complete physical examination, and surgery was then performed to resect all of the tumors. All tumors expressed human papillomavirus 18 no distant tumors were detected, and estrogen receptor and progesterone receptor testing were negative, suggesting that the cervix was the primary site.

CONCLUSION

This is the first report of a case of PSRCCC metastasis to bilateral ovaries only. Conservative management of human papillomavirus-associated type endocervical adenocarcinomas with independent ovarian metastases should be considered.

摘要

背景

原发性宫颈印戒细胞癌(PSRCCC)被定义为黏液癌。此前文献中尚未报道过伴有独立双侧卵巢转移的PSRCCC。

病例介绍

在此我们描述一例伴有卵巢受累的PSRCCC病例。患者接受了详细的全面体格检查,随后进行手术切除所有肿瘤。所有肿瘤均表达人乳头瘤病毒18型,未检测到远处肿瘤,雌激素受体和孕激素受体检测均为阴性,提示宫颈为原发部位。

结论

这是首例仅双侧卵巢转移的PSRCCC病例报告。对于伴有独立卵巢转移的人乳头瘤病毒相关型宫颈内膜腺癌应考虑保守治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d850/8001646/ce99b7d8e69c/OTT-14-2101-g0001.jpg

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