El-Sokkary Rehab, Kishk Rania, Mohy El-Din Sally, Nemr Nader, Mahrous Nageh, Alfishawy Mostafa, Morsi Samar, Abdalla Wael, Ahmed Mohamed, Tash Rehab
Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Microbiology and Immunology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.
Infect Drug Resist. 2021 Mar 25;14:1209-1218. doi: 10.2147/IDR.S299453. eCollection 2021.
The problem of antimicrobial resistance (AMR) is rising worldwide. One of the most significant factors influencing antimicrobial resistance in low- and middle-income countries is the lack of the skills and knowledge of health care providers for proper antimicrobial use.
To identify knowledge, characterize practices and describe the attitude of Egyptian prescribers towards antibiotic use.
A self-administered validated questionnaire was distributed among Egyptian prescribers.
Five hundred Egyptian physicians responded to the questionnaire, 113 (22.6%) reported having Antibiotic Stewardship Program (ASP) at their workplace, 99 (19.8%) use international antibiotic guidelines as the main source for prescribing activity, 358 (71.6%) recorded adequate knowledge. Elder prescribers and those who work in private or university hospitals were significantly more knowledgeable (p=0.031 and 0.001, respectively). Forty-seven (9.4%) showed a positive attitude towards proper antibiotic prescription. The type of work institution; primary health clinics and private, or university hospital and the specialty are significantly associated with a positive attitude (p=0.009 and 0.015, respectively). Seventy-eight (15.6%) expressed a proper antibiotic prescription practice. Elder age, more experienced and trained prescribers showed more proper practice. The implementation of ASP and using proper sources of information were significantly associated with proper practice (p=0.012 and 0.008, respectively).
Egyptian prescribers have a good level of knowledge about antibiotics. However, low rates of positive attitude and proper practice towards the problem of AMR and ASP are recorded.
抗菌药物耐药性（AMR）问题在全球范围内日益严重。影响低收入和中等收入国家抗菌药物耐药性的最重要因素之一是医疗保健提供者缺乏正确使用抗菌药物的技能和知识。
确定埃及处方医生对抗生素使用的知识、特征及态度。
向埃及处方医生发放一份经过验证的自填式问卷。
500名埃及医生回复了问卷，113名（22.6%）报告其工作场所设有抗生素管理计划（ASP），99名（19.8%）将国际抗生素指南作为处方活动的主要信息来源，358名（71.6%）具备足够的知识。年长的处方医生以及在私立或大学医院工作的医生知识更丰富（分别为p = 0.031和0.001）。47名（9.4%）对正确开具抗生素处方持积极态度。工作机构类型（基层医疗诊所、私立或大学医院）以及专业与积极态度显著相关（分别为p = 0.009和0.015）。78名（15.6%）表现出正确的抗生素处方行为。年长、经验更丰富且经过培训的处方医生表现出更正确的行为。ASP的实施以及使用正确的信息来源与正确行为显著相关（分别为p = 0.012和0.008）。
埃及处方医生对抗生素有较好的知识水平。然而，对抗菌药物耐药性和ASP问题持积极态度及正确行为的比例较低。
