Tomar Balvir S, Singh Mahaveer, Nathiya Deepak, Sharma Abhishek, Sharma Eshan, Bareth Hemant, Suman Supriya, Ruparelia Darshan Purshotambhai, Patel Jaykumar Bharatbhai, Gajera Vikrant Kantilal
Institute of Gastroenterology, Hepatology & Transplant, Nims University Rajasthan, Jaipur, India.
Department of Endocrinology, National Institute of Medical Sciences and Research Hospital, Nims University Rajasthan, Jaipur, 303121, India.
Int J Gen Med. 2021 Mar 25;14:1069-1078. doi: 10.2147/IJGM.S295499. eCollection 2021.
To assess the prevalence of post-COVID symptoms in patients with recovered COVID-19 (nasopharyngeal RT PCR negative) who were discharged from an acute COVID care facility at a tertiary care teaching hospital in North India.
This study was an observational study with retrospective data collection, conducted in the COVID follow-up clinic, a combined clinic of medicine and endocrinology. Patients discharged from the acute COVID care facility were recruited after 14 days of discharge if they fulfilled inclusion and exclusion criteria. The retrospective data was collected from the hospital records/EMR and analysed by the SPSSv23.
Fifty patients, who fulfilled the inclusion and exclusion criteria, were included in the study. The Mean age of patients was 53.4±13.8 years (range 28-77). Seventy six percent were male, and 38% had type 2 diabetes. Fever (94%), cough (78%) and breathlessness (68%), were the most common symptoms at presentation to acute care facility. Oxygen saturation at presentation had a negative correlation with D-Dimer, age, and C reactive protein. When patients were evaluated clinically, after 14 days (range 15 to 50 days) of the discharge, 82% of patients had at least one persistent symptom. Fatigue (74%) was the most common symptoms in follow-up followed by breathlessness (44%), and muscle weakness (36%). Two patients had persistent fever, even after negative RT PCR status.
Patients discharged from the acute COVID care facility had a high prevalence of post-COVID symptoms even after 14 days.
评估在印度北部一家三级护理教学医院的急性新冠护理机构出院的新冠康复患者（鼻咽RT-PCR检测阴性）中新冠后症状的患病率。
本研究是一项采用回顾性数据收集的观察性研究，在新冠随访诊所（一个内科和内分泌科联合诊所）进行。从急性新冠护理机构出院的患者在出院14天后，如果符合纳入和排除标准则被招募。回顾性数据从医院记录/电子病历中收集，并通过SPSSv23进行分析。
50名符合纳入和排除标准的患者被纳入研究。患者的平均年龄为53.4±13.8岁（范围28-77岁）。76%为男性，38%患有2型糖尿病。发热（94%）、咳嗽（78%）和呼吸困难（68%）是就诊于急性护理机构时最常见的症状。就诊时的血氧饱和度与D-二聚体、年龄和C反应蛋白呈负相关。当患者在出院14天（范围15至50天）后进行临床评估时，82%的患者至少有一种持续症状。疲劳（74%）是随访中最常见的症状，其次是呼吸困难（44%）和肌肉无力（36%）。两名患者即使RT-PCR检测呈阴性仍持续发热。
即使在出院14天后，从急性新冠护理机构出院的患者中新冠后症状的患病率仍很高。
