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埃塞俄比亚本尚古勒-古穆兹州公立医院结核病中心接受抗逆转录病毒治疗的逆转录病毒感染患者失访的影响

Influence of Lost to Follow Up from Antiretroviral Therapy Among Retroviral Infected Patients at Tuberculosis Centers in Public Hospitals of Benishangul-Gumuz, Ethiopia.

作者信息

Degavi Girish

机构信息

BuleHoraUniversity's Department of Nursing, College of Health and Medical Science, Bulehora, Hageremaryam, Ethiopia.

出版信息

HIV AIDS (Auckl). 2021 Mar 22;13:315-327. doi: 10.2147/HIV.S306257. eCollection 2021.

Abstract

BACKGROUND

Broadening access to healthcare (ART) antiretroviral therapy has led to a 19% reduction in the death rate of people infected with the human immunodeficiency virus. This study would also describe the status and deciding factors of ART in (TB) tuberculosis centers in public hospitals of Benishangul-Gumuz, Ethiopia, for (LTFU) lost follow-up among (RVI) retroviral infected patients.

METHODS

Hospital-based, unrivalled analysis of the case management (3:1) design was conducted. A total of 752 study participants (563 controls and 189 cases) Picked by systematic random sampling methodology, and where reviewed their charts from TB Centers. Data were entered and cleaned using Epi data version 3.1.1 and then exported to SPSS version 22 for analysis. To analyze the statistical relationship between the outcome variable and independent variables, binary logistic regression was used. Relevance was declared at a p-value <0.05.

RESULTS

A total of 1122 (25.3%) were LTFU. Among index cases with male cases, there were higher odds of lost to follow up (AOR= 1.68, 95% CI; 1.085, 2.609), 15-24 old age group have no formal education, civil servant were also having high comparatively. In index cases with identified parents, the risk of LTFU up had lower HIV status (AOR=0.5; 95% CI; 0.24, 0.997). Rest all variables showed low odds to LTFU.

CONCLUSION

A large number of patients enrolled in ARTwere missing from follow-up at TB centers, but unfortunately did not make the next appointment reported. The absence of prophylaxis was accepted as an independent determinant of LTFUfor ART.

摘要

背景

扩大医疗保健(抗逆转录病毒疗法)抗逆转录病毒治疗的可及性已使感染人类免疫缺陷病毒的人的死亡率降低了19%。本研究还将描述埃塞俄比亚贝尼尚古尔-古穆兹公立医院结核病中心抗逆转录病毒疗法的现状及决定因素,针对逆转录病毒感染患者中的失访情况。

方法

采用基于医院的、无与伦比的病例管理(3:1)设计分析。通过系统随机抽样方法选取了752名研究参与者(563名对照和189例病例),并查阅了他们在结核病中心的病历。使用Epi数据3.1.1版本录入和清理数据,然后导出到SPSS 22版本进行分析。为分析结果变量与自变量之间的统计关系,采用二元逻辑回归。p值<0.05时具有相关性。

结果

共有1122人(25.3%)失访。在索引病例中,男性病例失访的几率更高(调整后比值比=1.68,95%置信区间;1.085,2.609),15 - 24岁年龄组且未接受过正规教育的人群以及公务员失访几率也相对较高。在有明确父母的索引病例中,失访风险较高的患者艾滋病毒感染状况较低(调整后比值比=0.5;95%置信区间;0.24,0.997)。其余所有变量显示失访几率较低。

结论

大量登记接受抗逆转录病毒疗法的患者在结核病中心失访,但遗憾的是未报告下次预约情况。未进行预防被认为是抗逆转录病毒疗法失访的一个独立决定因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50d2/7997948/486f5191fb0d/HIV-13-315-g0001.jpg

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