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6日龄新生儿出现持续2天的血尿伴双侧肾上腺出血:病例报告

Bilateral Adrenal Hemorrhage in a 6-Day-Old Neonate Presenting with Hematuria of 2 Days Duration: Case Report.

作者信息

Tilahun Tsion, Diriba Gezahegn, Berhane Melkamu

机构信息

Department of Pediatrics and Child Health, Jimma University, Jimma, Ethiopia.

出版信息

Int Med Case Rep J. 2021 Mar 25;14:183-185. doi: 10.2147/IMCRJ.S294475. eCollection 2021.

DOI:10.2147/IMCRJ.S294475
PMID:33790660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8007555/
Abstract

BACKGROUND

The adrenal gland of newborns is susceptible to hemorrhage because of its relative larger size and high vascularity. Adrenal hemorrhage is bilateral in 10% of the cases. Neonates with adrenal hemorrhage present with anemia, jaundice, abdominal mass, and, rarely, adrenal insufficiency.

CASE DETAIL

A 6-day-old macrosomic neonate presented with hematuria of 2 days duration. Delivery was difficult. Abdominal ultrasound demonstrated bilateral suprarenal echo complex mass (right 4.3 cm by 2.2 cm and left 4 cm by 2 cm) and abdominal CT scan showed bilateral hypo-dense non-enhancing fluid-attenuated suprarenal gland masses (right 4.3 cm by 2.5 cm and left- 3.9 cm by 2.4 cm).

CONCLUSION

Adrenal hemorrhage should be considered and looked for in at-risk newborns like those with macrosomia, overwhelming sepsis, and perinatal asphyxia as well as those with bleeding diathesis. Although rare, hematuria is one of the clinical features of adrenal hemorrhage in neonates. Asymptomatic neonates with adrenal hemorrhage may not need any intervention except close follow up.

摘要

背景

新生儿肾上腺因其相对较大的体积和丰富的血管而容易发生出血。10%的病例中肾上腺出血为双侧性。患有肾上腺出血的新生儿表现为贫血、黄疸、腹部肿块,很少出现肾上腺功能不全。

病例详情

一名6日龄巨大儿新生儿出现持续2天的血尿。分娩困难。腹部超声显示双侧肾上腺回声复合性肿块(右侧4.3厘米×2.2厘米,左侧4厘米×2厘米),腹部CT扫描显示双侧低密度、无强化、液体衰减的肾上腺肿块(右侧4.3厘米×2.5厘米,左侧3.9厘米×2.4厘米)。

结论

对于有风险的新生儿,如巨大儿、严重脓毒症、围产期窒息以及有出血倾向者,应考虑并检查是否存在肾上腺出血。血尿虽罕见,但却是新生儿肾上腺出血的临床特征之一。无症状的肾上腺出血新生儿除密切随访外可能无需任何干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac70/8007555/beeb69aee0a4/IMCRJ-14-183-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac70/8007555/beeb69aee0a4/IMCRJ-14-183-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ac70/8007555/beeb69aee0a4/IMCRJ-14-183-g0001.jpg

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本文引用的文献

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Endocrinol Diabetes Metab Case Rep. 2018 Feb 20;2018. doi: 10.1530/EDM-17-0165. eCollection 2018.
2
Neonatal adrenal hemorrhage presenting as "Acute Scrotum"-looking beyond the obvious: a sonographic insight.表现为“急性阴囊”的新生儿肾上腺出血——透过表象深入观察:超声检查的见解
J Ultrasound. 2017 Apr 28;20(3):253-259. doi: 10.1007/s40477-017-0248-3. eCollection 2017 Sep.
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Adrenal bleeding in neonates: report of 37 cases.
新生儿肾上腺出血:37例报告
Turk J Pediatr. 2011 Jan-Feb;53(1):43-7.
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Massive adrenal haemorrhage in the newborn.新生儿肾上腺大量出血。
Arch Dis Child. 1959 Apr;34(174):178-82. doi: 10.1136/adc.34.174.178.
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Natural history of adrenal haemorrhage in the newborn.新生儿肾上腺出血的自然病史。
Arch Dis Child. 1973 Mar;48(3):183-90. doi: 10.1136/adc.48.3.183.