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急性呼吸困难患者死亡率的社会经济和临床预测因素

Socioeconomic and Clinical Predictors of Mortality in Patients with Acute Dyspnea.

作者信息

Wessman Torgny, Tofik Rafid, Ruge Thoralph, Melander Olle

机构信息

Department of Emergency Medicine, Skåne University Hospital, Malmö, Sweden.

Department of Clinical Sciences, Lund University, Malmö, Sweden.

出版信息

Open Access Emerg Med. 2021 Mar 25;13:107-116. doi: 10.2147/OAEM.S277448. eCollection 2021.

Abstract

BACKGROUND

Factors predicting long-term prognosis in patients with acute dyspnea may guide both acute management and follow-up. The aim of this study was to identify socioeconomic and clinical risk factors for all-cause mortality among acute dyspnea patients admitted to an Emergency Department.

METHODS

We included 798 patients with acute dyspnea admitted to the ED of Skåne University Hospital, Malmö, Sweden from 2013 to 2016. Exposures were living in the immigrant-dense urban part of Malmö (IDUD), country of birth, annual income, comorbidities, smoking habits, medical triage priority and severity of dyspnea. Mean follow-up time was 2.2 years. Exposures were related to risk of all-cause mortality using Cox proportional hazard model.

RESULTS

During follow-up 40% died. In models adjusted for age and gender, low annual income, previous or ongoing smoking, certain comorbidities, high medical triage priority and severe dyspnea were all significantly associated with increased mortality. After adjusting for age, gender and all significant exposures, the lowest quintile of income, ongoing or previous smoking, history of serious infection, anemia, hip fracture, high medical triage priority and severe dyspnea significantly and independently predicted mortality. In contrast, neither country of birth nor living in IDUD predicted a mortality risk.

CONCLUSION

Apart from several clinical risk factors, low annual income predicts two-year mortality risk in patients with acute dyspnea. This is not the case for country of birth and living in IDUD. Our results underline the wide range of mortality risk factors in acute dyspnea patients. Knowledge of patients' annual income as well as certain clinical features may aid risk stratification and determining the need of follow-up both in hospital and after discharge from an ED.

摘要

背景

预测急性呼吸困难患者长期预后的因素可指导急性治疗和随访。本研究的目的是确定急诊科收治的急性呼吸困难患者全因死亡的社会经济和临床风险因素。

方法

我们纳入了2013年至2016年在瑞典马尔默斯科讷大学医院急诊科收治的798例急性呼吸困难患者。暴露因素包括居住在马尔默移民密集的城市区域(IDUD)、出生国家、年收入、合并症、吸烟习惯、医疗分诊优先级和呼吸困难的严重程度。平均随访时间为2.2年。使用Cox比例风险模型将暴露因素与全因死亡风险相关联。

结果

随访期间40%的患者死亡。在根据年龄和性别调整的模型中,低年收入、既往或当前吸烟、某些合并症、高医疗分诊优先级和严重呼吸困难均与死亡率增加显著相关。在根据年龄、性别和所有显著暴露因素进行调整后,收入最低五分位数、当前或既往吸烟、严重感染史、贫血、髋部骨折、高医疗分诊优先级和严重呼吸困难显著且独立地预测了死亡率。相比之下,出生国家和居住在IDUD均未预测死亡风险。

结论

除了几个临床风险因素外,低年收入可预测急性呼吸困难患者的两年死亡风险。出生国家和居住在IDUD则不然。我们的结果强调了急性呼吸困难患者广泛的死亡风险因素。了解患者的年收入以及某些临床特征可能有助于进行风险分层,并确定在医院以及急诊科出院后随访的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd27/8008092/f111a4898eb8/OAEM-13-107-g0001.jpg

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