Department of Orthopedics, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang 310012, China.
Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China.
J Healthc Eng. 2021 Mar 13;2021:5585676. doi: 10.1155/2021/5585676. eCollection 2021.
If chronic osteomyelitis is not treated promptly and thoroughly, the wound will not heal for a long time, and the affected limb will be dysfunctional or disabled. In severe cases, it may even require amputation. In this article, a total of 50 patients with chronic osteomyelitis who meet the inclusion criteria were selected from January 2019 to March 2020 and were divided into two groups based on patient compliance, namely, a treatment group and a control group. The results of this group of studies showed that osteomyelitis is mostly manifested as limited diffusion, showing high signal on DWI, and ADC value is significantly higher than that of normal bone area. The normal bone area did not show obvious focal abnormal signals on the conventional MRI image. The ADC value of the measured patient's osteomyelitis area was compared with the ADC value of the normal bone area. The ADC value was significantly higher than that of the normal bone area, and the difference was statistically significant. Studies have shown that membrane induction technology is superior to the bone handling group in terms of limb function scores and results satisfaction in the treatment of chronic osteomyelitis bone defects. Membrane induction technology has a low complication rate, a small number of X-ray examinations, a short healing time, and a high functional score. However, bone handling technology has a long treatment process, long fixation time and healing time, nail channel infection, joint stiffness, nerve damage, and many other complications.
如果慢性骨髓炎不能及时、彻底地治疗，伤口将长时间不愈合，受影响的肢体将功能失调或残疾。在严重的情况下，甚至可能需要截肢。在本文中，我们从 2019 年 1 月至 2020 年 3 月共选择了 50 名符合纳入标准的慢性骨髓炎患者，根据患者的依从性将其分为两组，即治疗组和对照组。该组研究结果表明，骨髓炎多表现为局限性扩散，DWI 呈高信号，ADC 值明显高于正常骨区。常规 MRI 图像上未见正常骨区有明显局灶性异常信号。测量患者骨髓炎区域的 ADC 值与正常骨区域的 ADC 值进行比较，骨髓炎区域的 ADC 值明显高于正常骨区域，差异有统计学意义。研究表明，在治疗慢性骨髓炎骨缺损方面，膜诱导技术在肢体功能评分和结果满意度方面优于骨处理组。膜诱导技术具有并发症发生率低、X 线检查次数少、愈合时间短、功能评分高等优点。但是，骨处理技术的治疗过程长，固定时间和愈合时间长，钉道感染、关节僵硬、神经损伤等并发症较多。
