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聚甲基丙烯酸甲酯(PMMA)在治疗半侧颜面短小畸形病例中的应用

Polymethyl Methacrylate (PMMA) in the Treatment of a Case of Hemifacial Microsomia.

作者信息

Milhomem Anália Cirqueira, Jorge Isabella Mendes de Souza, da Costa Eduardo Luiz, Vinaud Marina Clare, Lino Júnior Ruy de Souza

机构信息

Tropical Pathology and Public Health Institute, Federal University of Goias, Goiânia, GO, Brazil.

Medicine School of Federal University of Goias, Goiânia, GO, Brazil.

出版信息

Aesthet Surg J Open Forum. 2020 Jan 23;2(1):ojaa002. doi: 10.1093/asjof/ojaa002. eCollection 2020 Jan.

Abstract

Hemifacial microsomia (HMF) is a morphological alteration characterized by facial deformities. These alterations are a consequence of a congenital anomalous development of the first and second branchial arches. It may present a genetic or environmental origin or a mixture of both and is considered mostly multifactorial. The clinical presentation varies; however, some characteristics are predominant such as unilateral mandible hypoplasia, agenesis or malformation of the auricular pavilion, and agenesis or malformation of the eye globe. The aim of this paper was to report a clinical case of a patient with late diagnosis of HMF which presented multiple deformities and received treatment with polymethyl methacrylate (PMMA) implant in different concentrations. Aiming for facial harmony, the PMMA implant occurred in the following regions: canine fossa, nasolabial sulcus, mandible, Bichat Ball, chin outline, lip contour, nose base, columella, nose tip, and dorsum. The treatment resulted in significant improvement in the facial symmetry.

摘要

半侧颜面短小畸形(HMF)是一种以面部畸形为特征的形态学改变。这些改变是第一和第二鳃弓先天性异常发育的结果。它可能源于遗传或环境因素,或两者兼而有之,大多被认为是多因素导致的。临床表现各不相同;然而,一些特征较为突出,如单侧下颌骨发育不全、耳廓发育不全或畸形,以及眼球发育不全或畸形。本文的目的是报告一例HMF晚期诊断患者的临床病例,该患者存在多种畸形,并接受了不同浓度的聚甲基丙烯酸甲酯(PMMA)植入物治疗。为了实现面部和谐,PMMA植入物应用于以下区域:尖牙窝、鼻唇沟、下颌骨、颊脂垫、下颌轮廓、唇轮廓、鼻基底、鼻中隔、鼻尖和鼻背。治疗使面部对称性得到了显著改善。

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