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白内障超声乳化术后视网膜脱离的风险:一项关于白内障手术结局的全人群研究。

Risk for retinal detachment after phacoemulsification: a whole-population study of cataract surgery outcomes.

作者信息

Clark Antony, Morlet Nigel, Ng Jonathon Q, Preen David B, Semmens James B

机构信息

Eye and Vision Epidemiology Research Group, Centre for Population Health Research, Curtin Health Innovation Research Institute, Curtin University, Perth, Australia.

出版信息

Arch Ophthalmol. 2012 Jul;130(7):882-8. doi: 10.1001/archophthalmol.2012.164.

Abstract

OBJECTIVES

To estimate the long-term cumulative incidence of and risk factors for retinal detachment (RD) after phacoemulsification using linked administrative medical data.

METHODS

We used the Western Australian Data Linkage System to identify patients who underwent phacoemulsification in Western Australia between January 1989 and December 2001. Retinal detachment cases were those patients requiring admission for RD surgery after phacoemulsification that were validated by medical record review. Kaplan-Meier analysis was used to calculate a cumulative incidence. Cox proportional hazards regression modeling was used to determine the association between RD and risk factors, including patient demographics and operative and hospital factors. Some important risk factors, including axial length and Nd:YAG laser capsulotomy, were not examined.

RESULTS

We identified 237 RD cases following 65 055 phacoemulsification procedures, with a 10-year cumulative incidence of 0.68% (95% CI, 0.56%-0.83%). Significant risk factors were year of surgery (hazard ratio [HR], 0.43; 95% CI, 0.28-0.66 [1999-2001 compared with 1989-1993] for each 5-year period after 1985), age younger than 60 years (3.76; 2.83-5.00), male sex (1.91; 1.45-2.51), and anterior vitrectomy (27.60; 19.27-39.52). Hospital location, patient rural or remote locality, hospital cataract surgery volume, failed intraocular lens insertion, length of stay, and patient insurance status were not significantly associated with RD.

CONCLUSIONS

Risk for RD after phacoemulsification has almost halved for each 5-year period since its adoption in the mid 1980s. Younger patient age and male sex at surgery significantly increased risk for RD. Phacoemulsification requiring anterior vitrectomy vastly increased risk for RD.

摘要

目的

利用关联的行政医疗数据评估白内障超声乳化术后视网膜脱离(RD)的长期累积发病率及危险因素。

方法

我们使用西澳大利亚数据链接系统识别1989年1月至2001年12月期间在西澳大利亚接受白内障超声乳化手术的患者。视网膜脱离病例为白内障超声乳化术后因视网膜脱离手术而入院的患者,经病历审查确认。采用Kaplan-Meier分析计算累积发病率。采用Cox比例风险回归模型确定视网膜脱离与危险因素之间的关联,包括患者人口统计学特征以及手术和医院因素。一些重要的危险因素,如眼轴长度和钕:钇铝石榴石激光晶状体囊切开术未进行检查。

结果

我们在65055例白内障超声乳化手术中识别出237例视网膜脱离病例,10年累积发病率为0.68%(95%可信区间,0.56%-0.83%)。显著的危险因素包括手术年份(风险比[HR],0.43;95%可信区间,0.28-0.66[1999-2001年与1989-1993年相比,1985年后每5年为一个时间段])、年龄小于60岁(3.76;2.83-5.00)、男性(1.91;1.45-2.51)和前部玻璃体切除术(27.60;19.27-39.52)。医院位置、患者居住在农村或偏远地区、医院白内障手术量、人工晶状体植入失败、住院时间和患者保险状况与视网膜脱离无显著关联。

结论

自20世纪80年代中期采用白内障超声乳化术以来,每5年视网膜脱离风险几乎减半。手术时患者年龄较小和男性显著增加视网膜脱离风险。需要前部玻璃体切除术的白内障超声乳化术极大地增加视网膜脱离风险。

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