The University of Sydney, Sydney, NSW.
Concord Repatriation General Hospital, Sydney, NSW.
Med J Aust. 2021 Apr;214(7):310-317. doi: 10.5694/mja2.50997. Epub 2021 Mar 31.
To determine whether the availability of invasive coronary angiography at the hospital of presentation influences catheterisation rates for patients with acute coronary syndrome (ACS), and whether presenting to a catheterisation-capable hospital is associated with better outcomes for patients with ACS.
DESIGN, SETTING: Retrospective cohort study; analysis of Cooperative National Registry of Acute Coronary Events (CONCORDANCE) data.
SETTING, PARTICIPANTS: Adults admitted with ACS to 43 Australian hospitals (including 31 catheterisation-capable hospitals), February 2009 - October 2018.
Major adverse cardiovascular events (myocardial infarction, stroke, congestive heart failure, cardiogenic shock, cardiovascular death) and all-cause deaths in hospital and by six and 12- or 24-month follow-up.
The proportion of women among the 5637 patients who presented to catheterisation-capable hospitals was smaller than for the 2608 patients who presented to hospitals without catheterisation facilities (28% v 33%); the proportion of patients diagnosed with ST elevation myocardial infarction was larger (32% v 20%). The proportions of patients who underwent catheterisation (81% v 70%) or percutaneous coronary intervention (49% v 35%) were larger for those who presented to catheterisation-capable hospitals. The baseline characteristics of patients who underwent catheterisation were similar for both presentation hospital categories, as were rates of major adverse cardiovascular events and all-cause death in hospital and by 6- and 12- or 24-month follow-up.
Although a larger proportion of patients who presented to catheterisation-capable hospitals underwent catheterisation, patients with similar characteristics were selected for the procedure, independent of the hospital of presentation. Major outcomes for patients were also similar, suggesting equitable management of patients with ACS across Australia.
确定就诊医院是否提供有创冠状动脉造影术是否会影响急性冠状动脉综合征(ACS)患者的导管插入率,以及是否将患者转至能够进行导管插入术的医院是否与 ACS 患者的预后改善有关。
设计、地点:回顾性队列研究;对协同国家急性冠状动脉事件登记处(CONCORDANCE)数据进行分析。
地点、参与者:2009 年 2 月至 2018 年 10 月期间,43 家澳大利亚医院(包括 31 家具备导管插入术能力的医院)收治的 ACS 成年患者。
主要不良心血管事件(心肌梗死、卒、充血性心力衰竭、心源性休克、心血管死亡)和院内以及 6 个月、12 个月或 24 个月随访时的全因死亡。
在就诊于具备导管插入术能力医院的 5637 例患者中,女性比例(28%)小于就诊于无导管插入术设施医院的 2608 例患者(33%);诊断为 ST 段抬高型心肌梗死的患者比例(32%)较大。就诊于具备导管插入术能力医院的患者接受导管插入术(81%)或经皮冠状动脉介入治疗(49%)的比例较高。在这两种就诊医院类别中,接受导管插入术的患者的基线特征相似,院内及 6 个月、12 个月或 24 个月随访时的主要不良心血管事件和全因死亡发生率也相似。
尽管就诊于具备导管插入术能力医院的患者中接受导管插入术的比例较高,但患者的特征相似,这与就诊医院无关。患者的主要结局也相似,表明澳大利亚各地对 ACS 患者的管理公平。