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间歇心肌缺血的心脏康复作为难治性心绞痛的一种新治疗选择?

Cardiac rehabilitation with intermittent myocardial ischaemia as a new therapeutic option in refractory angina?

机构信息

Hôpital cardiologique Haut-Lévêque, Bordeaux University Hospital, Avenue de Magellan, Pessac, 33600, France.

Department of Cardiology, Felix Guyon Hospital, La Reunion University Hospital, Saint-Denis, Réunion, France.

出版信息

ESC Heart Fail. 2021 Jun;8(3):2316-2319. doi: 10.1002/ehf2.13335. Epub 2021 Mar 31.

DOI:10.1002/ehf2.13335
PMID:33792203
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8120403/
Abstract

A 72-year-old man daily suffered from a refractory angina consecutive to a diffuse coronary artery disease despite optimal medical management. Revascularization could not be performed because of a severe thrombopenia. He was referred to our outpatient cardiac rehabilitation programme where he was candidate for 20 sessions, three times a week, of high-intensity aerobic interval training involving brief episodes of regressive myocardial ischaemia. After 7 weeks, exercise capacity (+28.5%), VO peak (35.7%), and ischaemic threshold increased while clinical status and quality of life improved. No adverse effect was reported. Aerobic interval training with myocardial ischaemia might be a therapeutic alternative in refractory angina.

摘要

一位 72 岁男性尽管接受了最佳药物治疗,但仍每日遭受难治性心绞痛,原因是弥漫性冠状动脉疾病。由于严重的血小板减少症,无法进行血运重建。他被转介到我们的门诊心脏康复计划,在那里他有资格接受 20 次治疗,每周 3 次,每次包括短暂的退行性心肌缺血发作的高强度间歇有氧训练。7 周后,运动能力(增加 28.5%)、VO 峰值(35.7%)和缺血阈值增加,同时临床状况和生活质量改善。没有报告不良反应。伴有心肌缺血的间歇有氧训练可能是难治性心绞痛的一种治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab7/8120403/f989cbbba107/EHF2-8-2316-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab7/8120403/33936663801e/EHF2-8-2316-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab7/8120403/f989cbbba107/EHF2-8-2316-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab7/8120403/33936663801e/EHF2-8-2316-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab7/8120403/f989cbbba107/EHF2-8-2316-g002.jpg

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引用本文的文献

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本文引用的文献

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Coronary Collateral Growth Induced by Physical Exercise: Results of the Impact of Intensive Exercise Training on Coronary Collateral Circulation in Patients With Stable Coronary Artery Disease (EXCITE) Trial.运动诱导的冠状动脉侧支生长:强化运动训练对稳定性冠心病患者冠状动脉侧支循环影响的结果(EXCITE 试验)。
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Cardiac rehabilitation to improve physical functioning in refractory angina: a pilot study.心脏康复改善难治性心绞痛患者身体功能:一项试点研究。
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