Division of Cancer Medicine, The University of Texas MD Anderson Cancer, Houston, TX.
Department of Lymphoma/Myeloma, Division of Cancer Medicine, The University of Texas MD Anderson Cancer, Houston, TX.
Am Soc Clin Oncol Educ Book. 2021 Mar;41:1-7. doi: 10.1200/EDBK_320079.
Approximately 185,840 individuals will be diagnosed with hematologic malignancies in the United States in 2020. Disparities in disease incidence, prevalence, burden, mortality, and survivorship have been identified among this patient population. Contributing factors include genetic ancestry, race/ethnicity, sex, socioeconomic status, and geographic region. Historically, these inequities have been understudied. Addressing these disparities requires a systems-level approach, improving access to care and reducing biases in the clinical setting. Additional research is needed to construct comprehensive, multilevel models to explore systematic observational studies and perform strategic intervention trials to overcome these disparities.
预计 2020 年美国将有大约 185840 人被诊断患有血液系统恶性肿瘤。该患者群体的疾病发病率、患病率、负担、死亡率和生存率存在差异。造成这些差异的因素包括遗传背景、种族/民族、性别、社会经济地位和地理位置。从历史上看,这些不平等现象研究不足。解决这些差异需要采取系统层面的方法,改善医疗服务的可及性,并减少临床环境中的偏见。需要进一步研究来构建全面的多层次模型,以探索系统观察性研究,并进行战略干预试验,以克服这些差异。